Brain scans reveal how experimental drug may shift mood

NCT ID NCT05232032

Recruiting now Knowledge-focused Sponsor: Mclean Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests an experimental drug to see if it can fix brain patterns linked to avoiding rewards in people with major depression or anxiety. About 112 unmedicated adults will have brain scans and do decision-making tasks. The goal is to understand how the drug works, not to cure or treat the condition.

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Conditions

The condition(s) this trial relates to.

anxiety disorder generalized anxiety disorder major depressive disorder panic disorder post-traumatic stress disorder social phobia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ANXIETY DISORDER DEPRESSIVE DISORDER, MAJOR

Contacts and locations

Locations

Mclean Hospital
RECRUITING

Belmont, Massachusetts, 02478, United States

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