Breathing test may reveal who won't respond to anxiety therapy
NCT ID NCT05467683
First seen Jan 30, 2026 · Last updated Jun 20, 2026 · Updated 15 times
Summary
This study is testing whether a carbon dioxide (CO2) breathing challenge can identify people with anxiety, OCD, PTSD, or panic disorder who are unlikely to improve with exposure-based therapy. Researchers will give 600 adults a brief CO2 inhalation and measure their response, then track how well they do after 12 weeks of therapy. The goal is to develop a quick, easy biomarker that helps clinicians decide the best treatment approach from the start.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for POST-TRAUMATIC STRESS DISORDER are added.
By submitting, you agree to our Terms of use
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Boston University
RECRUITINGBoston, Massachusetts, 02215, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
The University of Texas at Austin
RECRUITINGAustin, Texas, 78712, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
carbon dioxide (CO2) inhalation challenge
What this could lead to
If successful, this could give doctors a simple test to decide whether exposure therapy is likely to work for a patient, saving time and pointing them toward better treatments sooner.
What could go wrong
This is an early-stage biomarker study, not a treatment trial. The CO2 test may not reliably predict therapy outcomes, and results may not apply to all patients or settings.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.