PANIC DISORDER

This study tests if a computer-delivered cognitive behavioral therapy can help people who have both an anxiety disorder and alcohol use disorder. The goal is to reduce heavy drinking and delay relapse. If effective, this program could be widely available at low cost. The study en…

This study tests whether delivering cognitive behavioral therapy (CBT) in person, via video, or a mix of both works best for children aged 5-18 with anxiety or OCD. About 500 participants will be randomly assigned to one of three delivery methods. The goal is to find ways to make…

This study tests whether an 8-week Mindful Self-Compassion training program can reduce symptoms of anxiety and depression. It compares delivering the program in-person versus through videoconference. The study involves 80 adults diagnosed with anxiety disorders or major depressio…

This study compares two care models for children and teens aged 8–17 with anxiety disorders. In stepped care, everyone starts with internet therapy and gets in-person therapy only if needed. In stratified care, participants are assigned to internet or in-person therapy based on t…

This study is testing a new internet-based therapy for young people aged 8 to 17 with anxiety disorders. The therapy is a type of talk therapy called cognitive behavioral therapy (CBT), delivered online over 12 weeks. The goal is to see if it reduces anxiety severity and to gathe…

This study looks at whether qigong (a gentle mind-body exercise) or multicomponent exercise (a mix of activities) can reduce panic and anxiety symptoms in people with panic disorder. Researchers will measure changes in panic severity, anxiety, balance, walking, sleep, fatigue, pa…

This study tests a new medicine, HB-1, to see if it safely reduces unexpected panic attacks in adults aged 18 to 65 with panic disorder. About 240 participants will receive either HB-1, a placebo, or another active drug. Researchers will track panic attack frequency and side effe…

This study is testing whether a carbon dioxide (CO2) breathing challenge can help predict which people with anxiety, OCD, PTSD, or panic disorder will not respond to exposure-based therapy. Researchers will enroll 600 adults aged 18 to 70. The goal is to see if this easy test can…

This study compares levels of certain immune-related proteins in the blood of people with panic disorder who have never taken medication and healthy volunteers. The goal is to see if these markers are different, which could help explain how inflammation might be linked to panic d…

This study tests whether using a life history calendar—a simple grid that helps people recall important life events—can improve how accurately adults in Hong Kong remember and report past mental health problems. Researchers will compare the standard interview method with the cale…