GENERALIZED ANXIETY DISORDER

This study tests whether a computer-assisted tool helps mental health providers in rural VA clinics deliver cognitive behavioral therapy (CBT) more effectively for depression and anxiety. About 34 therapists and 167 veterans will take part. Therapists are randomly assigned to use…

This pilot study tested a new type of brain stimulation, called accelerated intermittent theta burst stimulation (aiTBS), for people with anxiety disorders or PTSD. Fifteen participants received the non-invasive treatment targeting a novel brain area. The study measured changes i…

This study looked at whether different intensities of exercise can reduce anxiety in adults with anxiety disorders. 110 sedentary adults with high anxiety sensitivity were assigned to either low-intensity exercise or a program that gradually increased to high-intensity exercise o…

This study tested whether a 6-week group therapy program (cognitive behaviour therapy) could help reduce anxiety and stress in pregnant women and new mothers. 72 women from Manitoba, Canada, who were pregnant or within 12 months postpartum and had an anxiety disorder took part. T…

This study tested an internet-based cognitive behavioral therapy (CBT) program called AMTE for adolescents with anxiety and depression. Sixty teens were randomly assigned to either the online program or a control group. The goal was to see if the program could reduce symptoms of …

This study tested whether a 6-session educational program could help people receiving electroconvulsive therapy (ECT) feel less stigma and anxiety about their mental health treatment. Sixty adult inpatients with conditions like depression or bipolar disorder took part. Those who …

This study tested whether a 12-session parent-based treatment (Supportive Parenting for Anxious Childhood Emotions) can reduce anxiety in children by changing how their brains respond. 214 children with anxiety disorders participated. The goal was to see if parent training alone …

This study tested a device called cranial electrotherapy stimulation (CES) for treating generalized anxiety disorder in 130 young adults aged 18-21. Participants used the device at home for 60 minutes daily over six weeks. The goal was to see if CES reduces anxiety symptoms compa…

This study tested a type of therapy called Emotion Regulation Therapy - Attention Regulation (AR-ERT) to help people with obsessive-compulsive disorder, generalized anxiety disorder, or major depressive disorder who struggle with repetitive negative thinking. 65 adults in Massach…

This study tested a new anxiety program designed for autistic youth ages 7 to 17. The program was delivered in community care centers to make it more accessible. Researchers wanted to see if it was practical and helpful for reducing anxiety symptoms. The study involved 32 partici…

This study tested whether a gentle electrical current applied to the scalp (tDCS) can reduce symptoms of major depression, schizophrenia, OCD, generalized anxiety, and insomnia. 320 adults aged 16–65 received multiple sessions over weeks. Researchers measured symptom changes usin…

This study looked at whether using a person's DNA to pick an antidepressant works better than usual care for cancer patients with depression or anxiety. About 99 adults with cancer took part. Half got a DNA-guided choice of medication, and the other half got standard care. Resear…

This study tested a new way of delivering care for people with anxiety and depression in Danish general practices. 302 adults with conditions like panic disorder, social anxiety, or PTSD took part. The model involved a team of doctors, nurses, and therapists working together, and…

This study tested a new type of group therapy that combines standard cognitive behavioral therapy with religious values like gratitude and trust. Researchers compared it to regular therapy and a control group in 33 young adults with anxiety. The goal was to see if the faith-based…

This study tested whether a probiotic called Lactobacillus paracasei PS23 can reduce anxiety symptoms in adults with generalized anxiety disorder. Participants took either the probiotic or a placebo for a period, and researchers measured changes in anxiety levels, sleep, and gut …

This study tested a new medication called SEP-363856 in 434 adults with generalized anxiety disorder. Participants took either the drug or a placebo for up to 12 weeks. Researchers measured changes in anxiety symptoms using standard rating scales to see if the drug was safe and e…

This study tested a one-day life skills workshop for veterans with mild traumatic brain injury, chronic pain, and mental health conditions like PTSD and depression. The workshop taught coping strategies to reduce distress and improve reintegration into civilian life. 176 veterans…

This study tested a new drug called ENX-102 in 252 adults with generalized anxiety disorder. Participants received either the drug or a placebo for several weeks. Researchers measured changes in anxiety symptoms using a standard rating scale. The goal was to see if ENX-102 reduce…

This study tested whether an 8-week automated text-message therapy program could reduce anxiety in young adults aged 18-25. One hundred participants with elevated anxiety were randomly assigned to receive the text therapy or be placed on a waitlist. The goal was to see if this co…

This study tested a new program called Adjunctive Family-Cognitive Behavioral Therapy (AF-CBT) for veterans with anxiety disorders. It involved 48 veterans and their family members to see if adding family support to standard therapy was acceptable and helpful. The main goal was t…

This study looks at how the brains of children aged 9 to 12 with anxiety disorders respond to making mistakes. Researchers measure two types of brain activity: one after an error and one after a balance disturbance. Half of the children will use a 45-minute computer program desig…

This study looked at nearly 2,000 people from the community to understand how depression, anxiety, and migraine are passed down through families. Researchers interviewed family members of all ages, including children as young as 8, to track patterns of these conditions over time.…

This study looked at how the brain and heart respond to stressful images and sounds in women who have had multiple pregnancy losses and also have anxiety. Researchers used special head sensors and heart monitors to measure these reactions in 70 women. The goal was to find pattern…

This study looked at whether exercise helps adults with high anxiety and anxiety disorders (like generalized anxiety, panic, or social anxiety) better learn to unlearn fear. 54 participants either exercised or sat quietly after a fear-extinction task. Researchers measured skin sw…

This study tested whether a brain wave measurement called mismatch negativity (MMN) can help match veterans with mental illness to the most effective cognitive training program. 100 veterans with conditions like schizophrenia, PTSD, or mood disorders participated. The goal was to…

This study tested whether real-time fMRI neurofeedback can help people with anxiety disorders better regulate their emotions. 21 participants practiced cognitive reappraisal while receiving feedback on their prefrontal cortex activity. The goal was to understand the brain mechani…