New anxiety drug shows promise in early trial
NCT ID NCT05749055
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested a new drug called ENX-102 in 252 adults with generalized anxiety disorder. Participants received either the drug or a placebo for several weeks. Researchers measured changes in anxiety symptoms using a standard rating scale. The goal was to see if ENX-102 reduces anxiety better than a placebo and to check its safety.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
ENX-102 (a drug that targets GABA receptors in the brain to reduce anxiety)
What this could lead to
If successful, ENX-102 could offer a new treatment option for people with generalized anxiety disorder, potentially with fewer side effects than current medications.
What could go wrong
This is a Phase 2 trial with only 252 participants, so results may not hold up in larger studies. The drug may not work better than placebo, and side effects are still being evaluated.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for GENERALIZED ANXIETY DISORDER are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Accel Research Sites Network - Lakeland CRU
Lakeland, Florida, 33803, United States
-
Accel Research Sites Network - Maitland CRU
Maitland, Florida, 32751, United States
-
Aim Trials
Plano, Texas, 75093, United States
-
Alliance Research
Long Beach, California, 90712, United States
-
Alpine Research Organization
Clinton, Utah, 84015, United States
-
Anderson Clinical Research
Redlands, California, 92374, United States
-
Austin Clinical Trials Partners
Austin, Texas, 78737, United States
-
Baylor College of Medicine
Houston, Texas, 77030, United States
-
Boston Clinical Trials
Boston, Massachusetts, 02131, United States
-
California Neuroscience Research, LLC
Sherman Oaks, California, 91403, United States
-
CenExel iResearch, LLC
Savannah, Georgia, 31405, United States
-
Clinical Neuroscience Solutions, Inc.
Jacksonville, Florida, 32256, United States
-
Clinical Neuroscience Solutions, Inc.
Orlando, Florida, 32801, United States
-
Clinical Neuroscience Solutions, Inc.
Memphis, Tennessee, 38119, United States
-
Collaborative Neuroscience Research, LLC (CNS)
Garden Grove, California, 92845, United States
-
Collective Medical Research
Overland Park, Kansas, 66210, United States
-
Core Clinical Research
Everett, Washington, 98201, United States
-
Excell Research, Inc.
Oceanside, California, 92056, United States
-
FutureSearch Trials of Dallas
Dallas, Texas, 75231, United States
-
Grayline Research Center
Wichita Falls, Texas, 76309, United States
-
IMA Clinical Research
Las Vegas, Nevada, 89102, United States
-
IMA Clinical Research Phoenix
Phoenix, Arizona, 85012, United States
-
Mountain View Clinical Research
Denver, Colorado, 80209, United States
-
NRC Research Institute
Los Angeles, California, 90015, United States
-
Neurobehavioral Research
Cedarhurst, New York, 11516, United States
-
Pacific Clinical Research Management Group
Upland, California, 91786, United States
-
Precise Research Centres
Flowood, Mississippi, 39232, United States
-
Richmond Behavioral Associates
Staten Island, New York, 10314, United States
-
SPRI Clinical Trials, LLC
Brooklyn, New York, 11235, United States
-
Sun Valley Research Center
Imperial, California, 92251, United States
-
Sunwise Clinical Research
Walnut Creek, California, 94596, United States
-
Vertex Clinical Research
Clermont, Florida, 34711, United States