New therapy targets the Brain's 'Thought Loops' in OCD, anxiety, and depression
NCT ID NCT04225624
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a type of therapy called Emotion Regulation Therapy - Attention Regulation (AR-ERT) to help people with obsessive-compulsive disorder, generalized anxiety disorder, or major depressive disorder who struggle with repetitive negative thinking. 65 adults in Massachusetts received eight weekly therapy sessions focused on improving attention and cognitive control. The goal was to see if this approach could reduce unwanted thoughts and improve mental health.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Emotion Regulation Therapy - Attention Regulation (AR-ERT)
What this could lead to
If successful, this therapy could offer a new way to reduce repetitive negative thinking in people with OCD, anxiety, or depression.
What could go wrong
This is a small, early-stage trial with only 65 participants, so results may not apply to everyone. The therapy is behavioral and may not work for all individuals.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Massachusetts General Hospital
Boston, Massachusetts, 02114, United States