Could a single brain target treat depression, anxiety, and OCD at once?
NCT ID NCT06282146
First seen Jul 13, 2026 · Last updated Jul 14, 2026 · Updated 1 time
Summary
This early-phase trial tests a new brain stimulation target for people with depression plus at least one other psychiatric disorder, such as anxiety, OCD, or PTSD. The treatment uses a non-invasive form of brain stimulation called accelerated intermittent theta burst stimulation (aiTMS) aimed at the posterior parietal cortex. The main goal is to check safety and tolerability, while also exploring whether it improves symptoms and changes brain function.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- transcranial magnetic stimulation (TMS)
- What this could lead to
- If successful, this could point toward a new brain stimulation approach for treating multiple psychiatric conditions at once.
- What could go wrong
- This is a very early, small trial with only 10 participants, so results may not apply widely. Side effects like headache or neck pain are possible.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
-
Brigham and Women's Hospital
Boston, Massachusetts, 02115, United States
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