MENTAL DISORDER

This study tests a program called Tunawiri (meaning 'thrive') that adds mental health screening, counseling, and support to regular HIV care for pregnant and postpartum women in Kenya. The goal is to improve depression, anxiety, and HIV treatment success. Nine hundred women will …

This study is testing whether virtual reality (VR) training can help people with substance use and mental health disorders improve their social functioning and quality of life. Researchers will compare VR training plus standard care against standard care alone in 102 adults recei…

This study tests two self-care methods—virtual ear acupressure and Baduanjin qigong—to prevent or reduce period pain in 145 women aged 16–35 with primary dysmenorrhea. Participants will be randomly assigned to one of three groups and practice their assigned technique for 12 weeks…

This study tests a smartphone app called AMP-C that teaches people to notice and enjoy positive events. The goal is to see if it can reduce depression and cannabis use in adults who struggle with both. Eighty participants will either use the app or just track their symptoms. The …

This study tests a device that combines magnetic brain stimulation with cognitive exercises to see if it can improve thinking and memory in people with mild Alzheimer's disease. About 180 participants aged 60-85 will receive either real or sham stimulation along with real cogniti…

This study tests an AI chatbot called Aurora that guides people through creating a personal life story to improve emotional well-being and identity. It includes healthy adults, adults with mental health conditions in residential care, and older adults aged 65+. The chatbot is not…

This study tests a program called Healthy ReStart that uses health coaching, motivational interviewing, and online tools to help adults with serious mental illness return to active lives after major disruptions like the COVID-19 pandemic. Sixty participants will receive either th…

This study uses a non-invasive brain stimulation technique called TMS to see if it can change brain activity in people with schizophrenia. Researchers will measure brain waves before and after stimulation to understand how the hippocampus works in this condition. The goal is not …

This study uses transcranial magnetic stimulation (TMS) to map brain circuits in 180 adults with depression, OCD, anxiety, or schizophrenia. Participants receive accelerated TMS over two days while completing behavioral tests and questionnaires. The goal is to understand which br…

This study looks at how low oxygen levels (like at high altitudes) affect mood and anxiety in people with depression or anxiety disorders compared to healthy individuals. 68 participants will spend six hours in a special chamber that simulates 3,800 meters altitude, and their fee…

This study tests whether a radio-wave sensor placed in the home can measure sleep, movement, and walking speed in 40 people with mild cognitive impairment or mild Alzheimer's who are taking nicotinamide riboside (a form of vitamin B3). The goal is to find digital biomarkers that …

This observational study follows 300 adults receiving strategic psychotherapy—a short-term, goal-focused talk therapy—in private practice. Participants fill out questionnaires about their symptoms and well-being before and after treatment. The goal is to see if this therapy leads…

This pilot study is testing whether a simple saliva test can help doctors prescribe mental health medications more safely and effectively. 200 adults in Manitoba who are starting or changing psychiatric drugs will provide a DNA sample. The results will be shared with their doctor…