MENTAL DISORDER

This study looks at whether a team-based mental health program can help pregnant and new mothers living with HIV in Kenya feel better and stay healthy. About 900 women will receive extra mental health support alongside their regular HIV care. The goal is to reduce depression and …

This study tests a virtual reality (VR) program designed to help people with substance use and mental health disorders improve their social functioning. About 102 adults in long-term addiction treatment will either receive VR training twice a week for five weeks plus usual care, …

This study tests a program that combines health coaching, motivational interviewing, and online wellness tools to help 60 adults with serious mental illness improve their health and daily functioning after major disruptions like the COVID-19 pandemic. Participants will work with …

This study tests a digital program called AMP-C for people who have both depression and cannabis use problems. About 80 adults will either use the AMP-C app or just track their symptoms. Researchers will check if the app improves mood, reduces cannabis use, and is easy to use.

This study tests a device called ATNC MDD-V1 that uses gentle magnetic pulses and brain exercises to improve thinking and memory in people with mild Alzheimer's. About 180 adults aged 60 to 85 who are already on stable Alzheimer's medication will receive either the real treatment…

This study looks at how being in a low-oxygen environment (like high altitude) affects mood and anxiety in people with depression or anxiety disorders, compared to healthy individuals. Participants spend six hours in a special chamber that simulates altitude, and researchers meas…

This study aims to understand how different parts of the brain's prefrontal cortex control behaviors in people with major depression, obsessive-compulsive disorder, generalized anxiety disorder, or schizophrenia. Participants will receive transcranial magnetic stimulation (TMS) a…

This study follows 300 adults getting strategic psychotherapy—a short, goal-focused therapy—in private practice. Participants fill out questionnaires about their symptoms and well-being before and after treatment. The goal is to see if this therapy leads to real-world improvement…

This study explores how a non-invasive brain stimulation technique called theta burst stimulation (TMS) affects brain activity in people with schizophrenia. Researchers aim to understand if they can safely target the hippocampus, a brain region linked to symptoms like delusions a…

This study is testing whether a simple genetic test can help doctors choose safer and more effective medications for people with mental health conditions. Researchers will enroll 200 adults in Manitoba who are starting or changing psychiatric drugs. The goal is to see if using ge…

This study aims to find digital markers of brain energy changes in people with mild cognitive impairment or early Alzheimer's. Researchers will use passive home sensors to measure sleep, movement, and walking speed over 12 weeks. Participants take a daily supplement called nicoti…