Spit test could take guesswork out of mental health prescriptions

NCT ID NCT06929533

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This pilot study is testing whether a simple saliva test can help doctors prescribe mental health medications more safely and effectively. 200 adults in Manitoba who are starting or changing psychiatric drugs will provide a DNA sample. The results will be shared with their doctor to guide drug choice and dosing. The study focuses on whether this approach is practical and acceptable, not yet on whether it improves health outcomes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Pharmacogenetic testing (saliva-based DNA test to guide medication choice)

What this could lead to

If successful, this could show that genetic testing helps doctors pick better mental health drugs with fewer side effects, paving the way for wider use.

What could go wrong

This is a small pilot study (200 people) focused on feasibility, not proof of effectiveness. Results may not apply to everyone, and the test may not improve outcomes.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

anxiety disorder bipolar disorder Depression Drug-Related Side Effects and Adverse Reactions mental disorder psychiatric disorder Psychological Well-Being Psychotic Disorders

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Shared Health Facilities

    NOT_YET_RECRUITING

    Winnipeg, Manitoba, R3C 3H8, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Manitoba College of Pharmacy

    RECRUITING

    Winnipeg, Manitoba, R3E 0T5, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Email: •••••@•••••