University Of Manitoba

This study tests whether a blood thinner (heparin) can help hospitalized pneumonia patients avoid severe complications like needing a breathing machine or ICU care. About 4000 adults will be randomly assigned to receive either heparin or standard blood clot prevention. The goal i…

This study looks at whether a minimally invasive procedure called MMA embolization can lower the chance of a subdural hematoma (a type of brain bleed) coming back. About 1000 adults with this condition will be treated and followed for 90 days. The goal is to see if the procedure …

This study tests if Dialectical Behavioral Therapy (DBT), which teaches mindfulness and coping skills, can help teens aged 14-17 with obesity improve their quality of life and manage weight to prevent type 2 diabetes. Participants will be randomly assigned to weekly group session…

This study tests whether different types of mild electrical brain stimulation, combined with thinking exercises, can improve memory and daily function in people with dementia. Two hundred participants will try several stimulation patterns over repeated 4-week cycles, with breaks …

This study tests whether different types of gentle electrical brain stimulation, combined with computer-based thinking exercises, can improve memory and thinking in people with dementia. About 100 older adults with mild to moderate dementia will receive either real or fake stimul…

This study tests a 4-week online course that teaches people how to manage parasomnias—unwanted events during sleep like sleep terrors, sleepwalking, and nightmares. The course provides education and self-management guidance. Researchers will measure if the course reduces how ofte…

This study compares two types of anesthesia—spinal and epidural—for people having liver surgery. The goal is to see if spinal anesthesia leads to better blood pressure control, less need for IV fluids, and similar pain relief, helping patients recover faster. About 128 adults und…

This study tests whether using a virtual reality (VR) headset with a guided meditation program during a vasectomy can lower pain, anxiety, and discomfort. About 90 adult men will be randomly assigned to either use VR or receive standard care. The goal is to see if VR can make the…

This study tests a gel called PluroGel on burn injuries to see if it helps wounds heal better and reduces the need for skin grafts. Twenty adults with similar burns on both arms or legs will have one limb treated with PluroGel and the other with standard dressing. The goal is to …

This study tests a gentle brain stimulation technique called tDCS to see if it can improve thinking and memory in people with Parkinson's disease who have mild cognitive issues. About 36 adults with Parkinson's will receive either real or fake stimulation over several sessions. T…

This study tests whether a handheld nitrous oxide canister (laughing gas) can safely reduce pain and anxiety during burn dressing changes. About 30 adult burn patients will try both the gas and standard pain medicine in a crossover design. The goal is to find a safer alternative …

This study tests a group mental health program for adults 55 and older who feel lonely, isolated, or have anxiety or depression. The program is delivered by phone or video and focuses on building coping skills. Researchers will compare it to usual community activities to see if i…

This study tests a new, non-invasive way to measure brain waves linked to anxiety using a device placed in the outer ear canal. Researchers will give healthy volunteers two different drugs that are known to reduce these brain waves and see if the ear device can detect the changes…

This study looks at how a gentle brain stimulation technique called HD-tDCS affects brain connections and blood flow. Researchers will test 100 healthy adults to understand these changes better. The goal is to improve future treatments for brain disorders.

This study follows up on children whose mothers had type 1 diabetes and took part in the CONCEPTT trial. Researchers will assess the children's thinking skills, behavior, and risk of autism using parent questionnaires. The goal is to understand how maternal diabetes during pregna…

This study aims to understand how using a medical fitness facility and daily habits like diet, exercise, and sleep affect health as people age. Researchers will collect information from 100 adults aged 30 and older who are members of the Wellness Institute in Manitoba. No treatme…

This study looks at whether a simple genetic test can help doctors choose safer and more effective medications for people with mental health conditions. Researchers will test 200 adults in Manitoba to see if the approach is practical and useful. The goal is to reduce trial-and-er…

This study aims to find genetic markers that may predict which children and youth (ages 6-24) with depression, anxiety, or OCD will experience behavioral activation—a side effect like restlessness or agitation—when taking SSRI antidepressants. Researchers will analyze DNA from 16…

This study looks at why many people who survive a serious illness in the ICU develop lasting muscle weakness. Researchers will test the heart and muscle function of 50 adults who were on a breathing machine for at least 7 days. The goal is to better understand how sepsis and crit…

This study is testing a new, non-invasive wearable device that creates maps of how the brain regulates its blood flow. Researchers will use the device on 250 healthy volunteers to see how it works and to learn how age and sex might affect this brain function. The goal is to gathe…