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Spinal zaps may help paralyzed patients exercise harder

NCT ID NCT07692191

Disease control Sponsor: University of Manitoba Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 09, 2026 · Last updated Jul 10, 2026 · Updated 1 time

Summary

This study tests whether a non-invasive technique called transcutaneous spinal electrical stimulation (TSES) can improve how well people with spinal cord injury respond to exercise. Participants will do cycling-like leg exercises with and without TSES to see if it boosts oxygen use, delays fatigue, and increases power output. The goal is to find ways to help people with SCI exercise more effectively and reduce their high risk of diseases like diabetes and heart disease.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
transcutaneous spinal electrical stimulation (TSES)
What this could lead to
If TSES improves exercise capacity, it could help people with spinal cord injury exercise more effectively, potentially lowering their risk of obesity, diabetes, and heart disease.
What could go wrong
This is a small, early-stage study (40 participants) testing immediate effects only. It may not show meaningful improvement, and results may not apply to all types of spinal cord injury.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 40 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jun 2024

Expected to finish

Oct 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 70 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * traumatic or non-traumatic spinal cord injury * Spinal cord injury of at least one year duration, C5 or lower, AIS A - D * medically stable and healthy enough to engage in and complete exercise requirements * willing and able to complete the exercise protocols and testing requirements * able to understand and follow written and verbal instructions from study staff * able to communicate with study staff about their exercise capabilities and preferences Exclusion Criteria: * current serious injury (ies) of the upper extremities * known cardiovascular disease * unsatisfactory results of EKG screening * implanted electronic cardiac devices (e.g., pacemaker, defibrillator, etc.) * current pressure ulcer(s) * morbid obesity * known thyroid dysfunction * current cancer * current uncontrolled high blood pressure * uncontrolled epilepsy * current deep vein thrombosis * ventilator dependency * cognitive impairment

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Conditions

The condition(s) this trial relates to.

cardiovascular disorder Motor Activity Obesity spinal cord injury spinal injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Spinal cord injuries (SCI) Spinal cord injury Spinal injury

How to take part

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  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

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Contacts and locations

Locations

  • University of Manitoba

    RECRUITING

    Winnipeg, Manitoba, R3E 0J9, Canada

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