University Of Manitoba

This study is testing a procedure called EMMA to treat chronic subdural hematomas, which are slow brain bleeds. The procedure aims to block the small blood vessels feeding the bleed to help it heal and prevent it from coming back. It will be tested in up to 1,000 patients in Cana…

This large international trial is testing whether giving hospitalized pneumonia patients a stronger, therapeutic dose of a common blood thinner (heparin) is better than the standard preventive dose at keeping them out of intensive care and helping them survive. The study aims to …

This study is testing whether different types of gentle electrical brain stimulation, when combined with memory exercises, can help people with dementia. Participants will receive four weeks of treatment followed by twelve weeks off, repeating this cycle with different stimulatio…

This study is testing whether a combination of gentle electrical brain stimulation and daily memory exercises can help improve thinking skills in people with dementia. Researchers will compare different types of stimulation to find the most effective approach for boosting memory …

This study is testing whether a home monitoring system can help people with advanced kidney disease avoid emergency room visits and hospital stays. About 340 patients will use a tablet app to track their blood pressure, weight, and symptoms daily, sharing the data with their care…

This study is testing whether people with chronic kidney disease can safely eat more potassium-rich fruits and vegetables. Researchers will provide 30 participants with home-delivered produce that is either high or low in potassium for six weeks each, then switch. The goal is to …

This study is testing if a special therapy that teaches emotional skills can help teens with obesity manage their weight and prevent type 2 diabetes. Researchers will compare teens who get this therapy plus lifestyle advice to those who get lifestyle advice alone or are in a cont…

This study compares two common anesthesia methods for patients having surgery to remove liver tumors. Researchers want to see if spinal anesthesia provides the same pain relief as epidurals while helping patients recover faster with fewer complications. They believe spinal anesth…

This study is testing whether a 4-week online educational course can help adults manage disruptive sleep behaviors like sleepwalking, night terrors, and nightmares. Researchers are comparing the course to basic sleep tips to see which is more effective at reducing how often these…

This study is testing if a widely available, inexpensive drug called tranexamic acid can safely reduce bleeding episodes in outpatients with serious blood cancers (MDS or AML). About 75 adult patients with low platelet counts will be randomly assigned to receive either the drug o…

This study is testing a group mental health program delivered by phone or video call for Canadians aged 55 and older who feel lonely, isolated, anxious, or depressed. It aims to see if this easy-to-access program improves people's ability to cope with difficult feelings and reduc…

This study aims to understand why people who survive a serious illness in the Intensive Care Unit (ICU) often have long-lasting muscle weakness and trouble exercising. Researchers will measure heart and lung fitness, as well as blood flow in the muscles, in 50 ICU survivors at 6 …

This study aims to understand if children born to mothers with type 1 diabetes are more likely to have differences in thinking skills, attention, or social behavior. Researchers are following up with 225 families from a previous pregnancy trial, asking parents to fill out questio…

This study aims to gather initial information to plan a larger, long-term research project on healthy aging. Researchers will collect detailed health and lifestyle data from 100 adults aged 30+ who are members of a specific wellness center. The goal is to understand the connectio…

This study aims to see if a non-invasive ear device can detect specific brain wave patterns linked to anxiety. Researchers will test 42 healthy volunteers, giving some anxiety-reducing drugs and others a placebo, while measuring signals from the ear canal and scalp. The goal is t…

This study is testing whether using a person's genetic information can help doctors in Manitoba choose more effective psychiatric medications with fewer side effects. It will enroll 200 adults whose doctors think this genetic testing could help with their treatment. The main goal…

This study aims to find genetic markers that can predict which children and young adults might experience a troubling side effect called 'behavioral activation' from common antidepressant medications (SSRIs). Researchers will compare the DNA of 160 young people (ages 6-24) who ei…

This study is testing a new, wearable device that uses light to create maps of how the brain controls its own blood flow. Researchers will use the device on 250 healthy volunteers to see how well it works and to learn how aging and biological sex might affect this process. The go…