University Of Manitoba
Clinical trials sponsored by University Of Manitoba, explained in plain language.
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Can canola oil tame metabolic syndrome?
Disease control CompletedThis study looked at whether replacing typical dietary fats with canola oil for 12 weeks could improve cholesterol, blood vessel function, and other heart disease risk factors in 80 adults with metabolic syndrome. Participants were men and women aged 20-75 with high LDL cholester…
Phase: NA • Sponsor: University of Manitoba • Aim: Disease control
Last updated May 15, 2026 11:56 UTC
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New hospital policy cuts blood transfusions in major surgeries
Disease control CompletedThis study tested a hospital-wide policy of giving a drug called tranexamic acid to patients undergoing major non-cardiac surgery. The goal was to see if it could reduce the need for blood transfusions. Over 8,400 adults took part across multiple hospitals. The study compared per…
Phase: PHASE4 • Sponsor: University of Manitoba • Aim: Disease control
Last updated May 13, 2026 16:00 UTC
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Pea protein vs. whey: which saves more muscle during dieting?
Disease control CompletedThis study looked at whether pea protein can help people with obesity keep their muscle mass while losing weight. About 60 adults aged 30 to 50 took part. Researchers compared the effects of pea protein and whey protein on muscle size and strength.
Phase: NA • Sponsor: University of Manitoba • Aim: Disease control
Last updated Apr 30, 2026 15:49 UTC
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New CT scan may sharply improve bleeding detection after stroke
Diagnosis CompletedThis study looked at whether a special type of CT scan (dual-energy CT) can more accurately tell the difference between bleeding and harmless contrast dye after stroke treatment. About 189 adults who had a stroke and received clot-busting drugs or a clot-removal procedure took pa…
Phase: NA • Sponsor: University of Manitoba • Aim: Diagnosis
Last updated May 17, 2026 02:16 UTC
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Video games help stroke and spinal injury patients regain hand control
Symptom relief CompletedThis study tested a fun, computer game-based exercise program to help people with stroke or spinal cord injury improve hand and arm movement. 35 adults who had a stroke or spinal injury at least six months earlier played specially designed games using a device that works like a c…
Phase: NA • Sponsor: University of Manitoba • Aim: Symptom relief
Last updated May 17, 2026 02:07 UTC
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Group therapy shows promise for easing anxiety in new and expecting mothers
Symptom relief CompletedThis study tested a 6-week group therapy program (cognitive behaviour therapy) designed for women experiencing anxiety during pregnancy or the first year after childbirth. 72 women took part, with some receiving the therapy right away and others placed on a waitlist. The goal was…
Phase: NA • Sponsor: University of Manitoba • Aim: Symptom relief
Last updated May 17, 2026 02:05 UTC
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Glue or stitches? new study tests faster circumcision recovery
Symptom relief CompletedThis study tested whether using skin glue (2-OCA) with a few stitches works as well as the usual continuous stitches for closing wounds after adult circumcision. Twenty men took part, and researchers measured pain, healing, complications, and how long the procedure took. The goal…
Phase: NA • Sponsor: University of Manitoba • Aim: Symptom relief
Last updated May 15, 2026 11:57 UTC
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Virtual writing therapy shows promise for PTSD in first responders
Symptom relief CompletedThis study tested if a therapy called Written Exposure Therapy (WET) can be done online in a group for military and police with PTSD. 29 people took part to see if the treatment was acceptable and if it reduced symptoms. The goal was to find a more accessible way to deliver care.
Sponsor: University of Manitoba • Aim: Symptom relief
Last updated May 14, 2026 12:02 UTC
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VR offers new hope for phantom limb pain after amputation
Symptom relief CompletedThis study looked at whether a virtual reality (VR) program is a practical and acceptable way to help people with phantom limb pain right after a leg amputation. Twenty participants tried the VR program daily for about 17 sessions, both in the hospital and at home. Researchers me…
Sponsor: University of Manitoba • Aim: Symptom relief
Last updated May 13, 2026 16:02 UTC
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Could a lower steroid dose be just as good for kids with croup?
Symptom relief CompletedThis study looked at whether a lower dose of the steroid dexamethasone works as well as the standard dose for treating croup in children. Croup is a viral infection that causes coughing and breathing trouble. The study involved 50 children and compared two doses. The goal is to f…
Phase: PHASE3 • Sponsor: University of Manitoba • Aim: Symptom relief
Last updated May 11, 2026 20:53 UTC
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New workshop helps chronic pain patients taper opioids safely
Symptom relief CompletedThis study tested a one-day educational workshop for 26 adults with chronic non-cancer pain who were taking high doses of opioids. The workshop, led by a team of psychologists, pharmacists, and doctors, taught about opioid risks and a coping strategy called Acceptance and Commitm…
Phase: NA • Sponsor: University of Manitoba • Aim: Symptom relief
Last updated May 11, 2026 20:49 UTC
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Breathing easy: new inhaler may ease pain during male scrotal procedures
Symptom relief CompletedThis study tested whether inhaling a pain-relief medicine called Penthrox (methoxyflurane) can help men feel less pain and anxiety during minor scrotal surgeries done with local anesthetic. Forty adult patients were randomly assigned to receive either local anesthetic alone or lo…
Phase: PHASE2 • Sponsor: University of Manitoba • Aim: Symptom relief
Last updated May 06, 2026 16:03 UTC
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Pedaling away dialysis discomfort: exercise study offers hope for symptom relief
Symptom relief CompletedThis study tested whether a 26-week exercise and education program could help people on long-term dialysis feel better. Researchers compared a group doing the program with a group receiving standard care to see if exercise reduced the burden of multiple symptoms and improved qual…
Phase: NA • Sponsor: University of Manitoba • Aim: Symptom relief
Last updated Apr 15, 2026 16:16 UTC
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New hope: class aims to reduce suicidal thoughts after an attempt
Knowledge-focused CompletedThis study tested a 12-week class called 'Living with Hope' that teaches coping skills to people who have recently attempted suicide. The goal was to see if the class could lower suicidal thoughts, hopelessness, and related symptoms. 26 adults who had made a suicide attempt in th…
Sponsor: University of Manitoba • Aim: Knowledge-focused
Last updated May 17, 2026 02:08 UTC
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Berry blood sugar boost? saskatoon study reveals glycemic impact
Knowledge-focused CompletedThis study looked at how dried Saskatoon berries and their powder affect blood sugar levels in 10 healthy adults. Researchers measured the glycemic index (a score of how fast a food raises blood sugar) for both forms of the berry. The goal is to provide clear dietary advice for p…
Phase: NA • Sponsor: University of Manitoba • Aim: Knowledge-focused
Last updated May 17, 2026 02:07 UTC
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Urine test may spot kidney rejection before damage is done
Knowledge-focused CompletedThis study looked at whether checking a substance in urine called CXCL10 could help doctors find kidney transplant rejection earlier. 260 adults who had a kidney transplant took part. The goal was to see if early treatment based on this test could help the new kidney work longer …
Phase: PHASE2, PHASE3 • Sponsor: University of Manitoba • Aim: Knowledge-focused
Last updated May 14, 2026 12:05 UTC
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Brain scans reveal how CBT skills may shield first responders from PTSD
Knowledge-focused CompletedThis study looked at whether a short course teaching cognitive behavioral therapy (CBT) skills can increase a brain pattern linked to resilience against PTSD. Researchers studied 30 public safety personnel (like police and firefighters) who were already in a larger trial. They us…
Phase: NA • Sponsor: University of Manitoba • Aim: Knowledge-focused
Last updated May 14, 2026 12:03 UTC
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Spinal anesthesia in heart valve surgery: a closer look at blood flow changes
Knowledge-focused CompletedThis study looked at 44 adults with severe heart valve problems (aortic stenosis or mitral regurgitation) who had valve replacement surgery. Researchers wanted to see how high spinal anesthesia changes blood flow and the need for drugs to keep the heart stable. The goal was to ga…
Sponsor: University of Manitoba • Aim: Knowledge-focused
Last updated May 13, 2026 16:03 UTC