University Of Manitoba

This study tested whether monitoring a substance in urine called CXCL10 can help detect kidney transplant rejection earlier. 260 adult kidney transplant patients were randomly assigned to either have their CXCL10 levels checked or receive standard care. If CXCL10 was high, patien…

This study tested a hospital policy of giving tranexamic acid to adults undergoing major non-cardiac surgery to reduce the need for blood transfusions. Over 8,400 patients took part across multiple hospitals. The goal was to see if this approach safely lowers transfusion rates an…

This study looked at whether eating canola oil every day for 12 weeks can improve cholesterol, blood vessel function, and other risk factors in people with metabolic syndrome. Eighty adults with the condition were randomly assigned to consume either canola oil or a typical Wester…

This pilot study tested whether pea protein can help people with obesity preserve muscle mass while losing weight, compared to whey protein. Sixty adults aged 30 to 50 followed a weight loss regimen and took either pea protein, whey protein, or a non-protein control. Researchers …

This study looked at whether a special type of CT scan (dual-energy CT) can more accurately tell the difference between bleeding and harmless contrast dye in the brains of stroke patients after treatment. About 189 adults who had a stroke and received clot-busting drugs or a clot…

This study tested whether a 6-week group therapy program (cognitive behaviour therapy) could help reduce anxiety and stress in pregnant women and new mothers. 72 women from Manitoba, Canada, who were pregnant or within 12 months postpartum and had an anxiety disorder took part. T…

This study tested a one-day educational workshop for people with chronic non-cancer pain who take high doses of opioids. The workshop, led by a team of doctors, psychologists, and pharmacists, provided information on opioid risks and taught coping strategies. Researchers wanted t…

This study looked at whether a 26-week exercise program, including home-based resistance training and cycling during dialysis, could reduce symptom burden and improve quality of life in 133 adults with end-stage kidney disease on chronic hemodialysis. Participants were assessed a…

This study looked at whether a virtual reality (VR) program is practical and acceptable for people who have phantom limb pain after a leg amputation. Twenty participants tried the VR program daily for about 17 sessions in the hospital, at home, or in therapy clinics. Researchers …

This study tested a computer game-based exercise program to help people with stroke or spinal cord injury improve hand and arm function. Thirty-five adults who were at least six months post-injury used a special mouse-like device to play games designed to practice hand movements.…

This study tested whether breathing in a pain-relief medicine called Penthrox (methoxyflurane) can help reduce pain and anxiety during urologic procedures done with local anesthetic. Forty adult men having procedures like hydrocelectomy or testicular biopsy took part. The goal wa…

This study tested a 12-week class called 'Living with Hope' for people who recently attempted suicide. The class teaches coping skills based on cognitive behavioral therapy (CBT). Researchers wanted to see if it could lower suicidal thoughts, hopelessness, and depression. The stu…

This study tested whether a 25% lower dose of dexamethasone (0.15 mg/kg) works as well as the standard dose (0.6 mg/kg) for treating croup in children. Croup is a viral infection that causes airway swelling and breathing trouble. The trial involved 50 children and tracked return …

This study tested whether Written Exposure Therapy, a treatment where people write about their traumatic experiences, can work when delivered virtually in a group setting. The participants were 29 military and police personnel with PTSD. The goal was to see if this approach is ac…

This pilot study tested whether using a medical glue (2-octyl cyanoacrylate) with just a few stitches is as good as the usual method of continuous stitching for closing wounds after adult circumcision. Twenty men were randomly assigned to one of the two closure methods. Researche…

This study looked at whether a 12-week cycling program during hemodialysis can reduce heart muscle stress (called stunning) in adults with end-stage kidney disease. 111 participants either cycled or rested during their dialysis sessions. Researchers measured heart function with u…

This small study tested whether a gentle brain stimulation technique called HD-tDCS could improve the effects of cognitive behavioral therapy (CBT) for people with depression, anxiety, or PTSD. Twenty participants received either real or fake stimulation daily for five weeks whil…

This study looked at whether a 5-session class teaching cognitive behavioral therapy (CBT) skills can increase a brain pattern linked to resilience against PTSD. It involved 30 public safety personnel (like police or firefighters) who were already in a larger study. Researchers u…

This completed study looked at how dried Saskatoon berries and their powder affect blood sugar levels in 10 healthy adults. Participants ate the berries or powder, and their blood sugar was measured over two hours. The goal is to determine the glycemic index of these berry produc…

This study looked at how spinal anesthesia changes blood flow and heart function in 44 patients with severe aortic stenosis or mitral regurgitation during valve replacement surgery. Researchers measured the need for drugs that support blood pressure and heart function, as well as…