Could a special gel help burn patients avoid skin grafts?
NCT ID NCT04893863
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This pilot study tests whether a gel called PluroGel®, used with standard dressings, can help burn injuries heal better and reduce the need for skin grafting. Twenty adults with similar burns on both arms or legs will have one limb treated with the gel and the other with standard care. The main goal is to see if the gel-treated area requires less grafting.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- PluroGel® (a gel dressing) plus moistened gauze, compared to standard topical antibiotic ointment and non-adherent gauze
- What this could lead to
- If it works, this could reduce the amount of skin grafting needed for burn injuries, leading to less scarring and fewer surgeries.
- What could go wrong
- This is a very small pilot study with only 20 people, so results may not apply broadly. The gel might not improve healing or could cause irritation.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University of Manitoba
RECRUITINGWinnipeg, Manitoba, R3A 1R9, Canada
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a dissolvable dressing get burn patients to skin grafts faster?
- Could a special dressing make skin grafts unnecessary for burns?
- Can tiny skin grafts heal wounds without leaving a second scar?
- Lab-Grown skin could transform burn healing
- Lab-Grown skin could transform burn care for children
- Can Lab-Grown skin permanently replace severe burn wounds?