Can Lab-Grown skin permanently replace severe burn wounds?

NCT ID NCT02350205

Recruiting now ⭐️ CURE ⭐️ Sponsor: CHU de Quebec-Universite Laval Source: ClinicalTrials.gov ↗

First seen Aug 05, 2026 · Last updated Aug 06, 2026 · Updated 1 time

Summary

This trial tests a lab-grown skin substitute made from a patient's own cells as a permanent replacement for severe burn wounds. It is for people with deep burns covering over half their body, where donor skin is scarce. The study compares how well this substitute grafts and heals compared to standard skin grafts, and evaluates scarring and safety.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Self-assembled skin substitute (SASS), a lab-grown skin graft made from the patient's own cells
What this could lead to: If successful, this could provide a permanent skin replacement for people with massive burns, reducing the need for repeated grafting and improving recovery.
What could go wrong: This is an early-stage trial, so the skin substitute may not take as well as hoped or could cause complications. Results from a small group may not apply to all burn patients.

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Conditions

The condition(s) this trial relates to.

burn

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BURNS

Contacts and locations

Locations

BC Children's Hospital Plastic Surgery Clinic
RECRUITING

Vancouver, British Columbia, V6H 3V4, Canada
CHU de Québec - Unité des grands brûlés
RECRUITING

Québec, Quebec, G1J 1Z4, Canada
Foothill Medcial Centre
RECRUITING

Calgary, Alberta, T2N 2T9, Canada
Hospital for Sick Children (Sickkids)
RECRUITING

Toronto, Ontario, M5G 1X8, Canada
Hôpital Sainte Justine
RECRUITING

Montreal, Quebec, H3T 1C5, Canada
Mackenzie Health Science's Centre
RECRUITING

Edmonton, Alberta, T6G 2B7, Canada
Vancouver General Hospital
RECRUITING

Vancouver, British Columbia, V5Z 1N1, Canada
Winnipeg Health Science Center
RECRUITING

Winnipeg, Manitoba, R3A 1R9, Canada

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