Chu De Quebec-universite Laval

This study looks at multiple myeloma patients who are receiving a newer kind of immunotherapy called a BCMA-directed T cell engager. These treatments can weaken the immune system and raise the risk of serious infections. The trial will compare two target levels of immunoglobulin …

This study tests whether adding bicalutamide (a drug used for prostate cancer) to standard BCG therapy can help prevent bladder tumors from coming back. It involves 160 men with early-stage bladder cancer who are already scheduled for BCG treatment. The goal is to see if the comb…

This study tests a new skin graft made from a patient's own cells, genetically modified to produce a missing protein that causes fragile skin in recessive dystrophic epidermolysis bullosa (RDEB). The graft is designed to be permanent and aims to heal wounds safely and effectively…

This study compares two types of radiation therapy for men with low- or intermediate-risk prostate cancer. One uses precise external beams (SBRT), the other uses tiny radioactive seeds placed inside the prostate (brachytherapy). The goal is to see which causes fewer urinary and b…

This study compares two types of radiation therapy for localized prostate cancer: a newer ultra-short course versus a standard shorter course, both combined with a precise internal radiation boost. Researchers want to see if the ultra-short approach causes fewer urinary and bowel…

This study tests if a special online group therapy program can help women with BRCA1/2 gene changes who have had breast or ovarian cancer feel less afraid of their cancer returning. About 250 women will either start therapy right away or wait. They will attend weekly online sessi…

This study compares a paravertebral nerve block to usual pain medication in 60 women having a mastectomy with immediate breast reconstruction. The goal is to see if the nerve block reduces pain in the first few days after surgery and may help prevent long-term chronic pain. Parti…

This study looks at whether a quick, painless test called capillaroscopy (examining tiny blood vessels at the base of the fingernails) can help doctors diagnose specific connective tissue diseases faster in people with an unclear autoimmune condition. About 40 adults with undiffe…

This study aims to see if a self-administered questionnaire can accurately capture family history and signs of rare genetic bone diseases in adults with osteoporosis. Researchers will compare the questionnaire results with detailed family trees (pedigrees) from 58 participants. T…