Prostate cancer radiation showdown: SBRT vs. brachytherapy

NCT ID NCT06052683

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This trial compares two types of radiation therapy for low-risk prostate cancer: SBRT (a precise, high-dose external beam treatment) and low-dose rate brachytherapy (implanting radioactive seeds). The goal is to see which causes fewer urinary and bowel side effects and leads to a better quality of life. About 208 men with low or favorable intermediate-risk prostate cancer will be randomly assigned to one of the two treatments.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

radiation therapy (SBRT or low-dose rate brachytherapy with Iodine-125 seeds)

What this could lead to

If it works, this could show that SBRT causes fewer urinary and bowel side effects than brachytherapy, helping doctors choose the gentler option.

What could go wrong

This is a medium-sized trial comparing two established treatments, so no major breakthrough is expected. Results may not apply to higher-risk cancers.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

prostate adenocarcinoma prostate cancer prostate carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Centre Intégré de Cancérologie, CHU de Québec-Université Laval

    RECRUITING

    Québec, Quebec, G1J 1Z4, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••