Lab-Grown skin patch could heal wounds in 'Butterfly Children'
NCT ID NCT07193134
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a new skin graft made from a patient's own cells, genetically modified to produce a missing protein. It aims to safely heal wounds in 9 people with recessive dystrophic epidermolysis bullosa (RDEB), a rare disease that causes fragile, blistering skin. The graft is applied after wound cleaning and temporary donor skin, and researchers will monitor healing, pain, and itching for a year.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
genetically modified skin graft made from the patient's own cells
What this could lead to
If it works, this could provide a lasting way to heal wounds and reduce pain and itching for people with RDEB.
What could go wrong
This is an early-phase trial with only 9 participants, so results may not apply to everyone. The graft uses a virus to modify cells, which carries unknown long-term risks.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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The Hospital for Sick Children (SickKids)
RECRUITINGToronto, Ontario, M5G 1E8, Canada
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••