Can a 5-Day radiation course beat the standard for prostate cancer?

NCT ID NCT05786742

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study tests whether a very short course of radiation (5 days) is as safe and effective as a longer course (2-3 weeks) for men with localized prostate cancer. All participants also receive a brachytherapy boost. The main goal is to compare side effects and quality of life over 5 years. About 205 men will take part.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
radiation therapy (ultra-hypofractionated vs. moderately hypofractionated) with HDR brachytherapy boost
What this could lead to
If successful, this could offer a shorter, more convenient radiation schedule for prostate cancer patients without increasing side effects.
What could go wrong
This is an early-phase study (phase 1-2) with a small number of participants. The ultra-short schedule may prove more toxic or less effective than standard treatment.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CHUdeQuebec

    RECRUITING

    Québec, G1R 2J6, Canada

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