Chu De Quebec-universite Laval

This study compares two radiotherapy schedules for men whose prostate cancer has returned after surgery. The standard treatment takes 5 weeks, while the shorter one takes 4 weeks. Researchers want to see if the shorter schedule causes no more side effects and controls the cancer …

This study tests a new skin graft made from a patient's own cells, genetically modified to produce a missing protein. It aims to safely heal wounds in 9 people with recessive dystrophic epidermolysis bullosa (RDEB), a rare disease that causes fragile, blistering skin. The graft i…

This study looks at whether giving extra antibodies (immunoglobulins) can help prevent serious infections in people with multiple myeloma who are being treated with a new kind of immunotherapy called a BCMA-directed T cell engager. About 80 adults who have already tried at least …

This study tests whether adding the drug bicalutamide to standard BCG therapy can help prevent bladder tumors from returning in men with non-muscle invasive bladder cancer. About 160 participants will be randomly assigned to receive either BCG alone or BCG plus bicalutamide. The …

This study tests whether a very short course of radiation (5 days) is as safe and effective as a longer course (2-3 weeks) for men with localized prostate cancer. All participants also receive a brachytherapy boost. The main goal is to compare side effects and quality of life ove…

This study tests a 4-week online cognitive-behavioral therapy (CBT) program for women with BRCA1/2 mutations who have finished cancer treatment and still worry a lot about cancer coming back. Researchers will compare those who get therapy right away to those on a waitlist, measur…

This study looks at whether a special nerve block (paravertebral block) can better control pain after a mastectomy with immediate breast reconstruction compared to usual pain medicines. About 60 women aged 18-70 will take part. The goal is to see if the nerve block reduces pain a…

This trial compares two types of radiation therapy for low-risk prostate cancer: SBRT (a precise, high-dose external beam treatment) and low-dose rate brachytherapy (implanting radioactive seeds). The goal is to see which causes fewer urinary and bowel side effects and leads to a…

Researchers are testing a 14-question survey to see if it can help detect rare genetic bone diseases (like osteogenesis imperfecta) in adults with osteoporosis. The study will enroll 58 participants who will fill out the online questionnaire. The goal is to see if the questionnai…

This study looks at whether a quick, painless test called capillaroscopy (examining tiny blood vessels at the fingernails) can help doctors diagnose specific connective tissue diseases sooner in people with an unclear autoimmune condition. About 40 adults with undifferentiated co…