Can tiny skin grafts heal wounds without leaving a second scar?

NCT ID NCT05223998

ENROLLING_BY_INVITATION Disease control Sponsor: The Metis Foundation Source: ClinicalTrials.gov ↗

First seen Aug 13, 2026 · Last updated Aug 14, 2026 · Updated 1 time

Summary

This trial tests a procedure that uses tiny full-thickness skin samples, called microcolumns, to cover open wounds. The goal is to see if this approach can help the wound heal while avoiding the extra scar that comes from traditional skin grafts. Participants are people aged 8 to 85 with open wounds on certain body areas that need coverage. The study will check how well the donor site heals and how the injured site recovers in terms of pigmentation, scarring, and pain.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Full-thickness skin microcolumns implantation (a surgical procedure)
What this could lead to: If successful, this approach could offer a way to cover wounds without creating a second scar, improving healing and cosmetic outcomes.
What could go wrong: This is a small early-stage proof-of-concept study, so results may not generalize. Risks include infection, poor graft take, or scarring.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

burn injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BURNS WOUND OF SKIN

Contacts and locations

Locations

The Center for Ambulatory Surgery of America

San Antonio, Texas, 78229, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.