Scientists map brain circuits with TMS to personalize mental health treatment

NCT ID NCT06376734

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study uses transcranial magnetic stimulation (TMS) to map brain circuits in 180 adults with depression, OCD, anxiety, or schizophrenia. Participants receive accelerated TMS over two days while completing behavioral tests and questionnaires. The goal is to understand which brain circuits control which behaviors, not to treat symptoms directly.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Transcranial magnetic stimulation (TMS)

What this could lead to

If successful, this could help personalize TMS therapy by targeting specific brain circuits for different mental health conditions.

What could go wrong

This is an early-phase mapping study, not a treatment trial. It may not lead to direct clinical benefits, and results may not apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

anxiety disorder Depression generalized anxiety disorder major depressive disorder mental disorder mood disorder obsessive-compulsive disorder psychiatric disorder schizophrenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Acacia Clinics

    RECRUITING

    Sunnyvale, California, 94087, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Brigham and Women's Hospital

    RECRUITING

    Boston, Massachusetts, 02115, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact