OCD

This study aims to improve access to effective therapy for children with anxiety and OCD by testing different delivery methods. It will compare weekly Cognitive Behavioral Therapy (CBT) delivered entirely in-person, entirely via telehealth video calls, or through a flexible mix o…

This study is testing if a gentle, non-invasive stimulation of a nerve in the ear (called tVNS) can make standard OCD therapy more effective. It will involve about 56 adults with moderate to severe OCD who will receive therapy sessions. Researchers will measure changes in OCD sym…

This study is testing a new, faster version of an approved brain stimulation treatment for depression and obsessive-compulsive disorder (OCD). The goal is to see if delivering the treatment over just 5 days can quickly improve symptoms. Researchers will also use brain scans to tr…

This study is testing a non-invasive brain stimulation technique to reduce symptoms of obsessive-compulsive disorder (OCD). Researchers will use a gentle electrical current applied to the scalp to target specific brain rhythms involved in reward and decision-making. The goal is t…

This study is testing whether a single session combining a non-invasive brain stimulation technique (rTMS) with training in emotion regulation skills can help people who struggle to calm down when upset. Researchers want to see if this combined approach changes brain activity and…

This early-stage study from Yale University is testing whether a single dose of psilocybin, the active compound in 'magic mushrooms,' is safe and tolerable for people whose daily lives are impacted by symptoms of depression, anxiety, trauma, or addiction. The study will enroll 50…

This study aims to find physical markers in the brain and body that can help doctors tell the difference between tics (from Tourette's) and compulsive behaviors (from OCD). Researchers will use portable EEG brain scans and smartwatches to record 50 participants both in a lab and …

This study aims to understand why some people with Obsessive-Compulsive Disorder (OCD) don't respond well to standard treatments. Researchers will use brain scans and thinking tests on 100 participants to look for patterns in brain activity. The goal is to find markers that could…

This research aims to understand if the timing of a common OCD therapy works better during certain phases of a woman's menstrual cycle. The study will use brain scans and hormone tests on 120 adults with OCD to see how hormones affect the brain's response to therapy. The goal is …