Can bringing family into therapy boost anxiety treatment for veterans?
NCT ID NCT05340478
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tested a new program called Adjunctive Family-Cognitive Behavioral Therapy (AF-CBT) for veterans with anxiety disorders. It involved 48 veterans and their family members to see if adding family support to standard therapy was acceptable and helpful. The main goal was to check if the program was feasible and satisfying, not to prove it works as a cure.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Adjunctive Family-Cognitive Behavioral Therapy (AF-CBT)
- What this could lead to
- If successful, this approach could make anxiety treatment more effective for veterans by involving their family members in therapy.
- What could go wrong
- This was a small feasibility study with only 48 participants and no control group, so results may not apply broadly. The therapy is an add-on, not a standalone treatment.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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48 people
The number who actually took part.
- Started
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Sep 2022
- Finished
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Apr 2024
- Lead sponsor
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A government agency
The lead sponsor is a US federal agency other than the NIH.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Veteran at least 18 years old; * current diagnosis of at least one anxiety-based disorder: PTSD, PD, SAD, or GAD (based on ADIS-5); * moderate-to-poor life enjoyment and satisfaction as indicated by a score of 47 or lower on the Q-LES-Q-SF * BAI score of 16 (moderate anxiety) or higher; * stable on psychotropic medication for 4 weeks before study participation; and * has a family member willing to participate in the study Exclusion Criteria: * Active symptoms of mania or psychosis at baseline (based on ADIS-5); * depression with active suicidal ideation/intent that would preclude treatment (based on ADIS-5 \& BAI); * moderate-to-severe cognitive impairment as indicated by a score below 20 on the SLUMS; * active drug/alcohol abuse during the initial 3-months of study enrollment (otherwise Veterans with comorbid substance/alcohol dependence are study eligible); and * undergoing concurrent transdiagnostic CBT for anxiety.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Michael E. DeBakey VA Medical Center, Houston, TX
Houston, Texas, 77030-4211, United States
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