Brain training shows promise for anxiety in small study

NCT ID NCT06132659

Completed Knowledge-focused Sponsor: University of Michigan Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether real-time fMRI neurofeedback can help people with anxiety disorders better regulate their emotions. 21 participants practiced cognitive reappraisal while receiving feedback on their prefrontal cortex activity. The goal was to understand the brain mechanisms behind emotion regulation, not to provide a treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: real-time fMRI neurofeedback
What this could lead to: If successful, this could point toward a way to improve emotion regulation training for anxiety disorders.
What could go wrong: This is a very small, early-stage study (21 people) focused on brain activity, not on treating symptoms. Results may not lead to a practical therapy.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

anxiety anxiety disorder generalized anxiety disorder hypochondriasis panic disorder social phobia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ANXIETY GENERALIZED ANXIETY DISORDER PANIC DISORDER SOCIAL ANXIETY DISORDER

Contacts and locations

Locations

University of Michigan

Ann Arbor, Michigan, 48109, United States

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