Brain zap trial aims to calm hearts in pregnancy loss anxiety

NCT ID NCT06968026

Completed Knowledge-focused Sponsor: Shenyang Jinghua Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 08, 2026 · Updated 2 times

Summary

This study explores whether a non-invasive brain stimulation technique called rTMS can change heart activity in women who have had multiple pregnancy losses and also suffer from anxiety. Fifty-five women will receive six different intensities of stimulation while their heart rate is monitored. The goal is to find which intensity produces the most noticeable heart-rate response, which could inform future research on potential treatments.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: repetitive transcranial magnetic stimulation (rTMS)
What this could lead to: If successful, this could identify a stimulation intensity that produces a measurable heart-rate response, guiding future studies on whether rTMS might help reduce anxiety or cardiovascular risk in this group.
What could go wrong: This is a very early, small proof-of-concept trial with only 55 participants and no treatment outcome measured. It only looks at immediate heart changes, not long-term benefits or safety, so it may not lead to any practical treatment.

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Conditions

The condition(s) this trial relates to.

anxiety disorder generalized anxiety disorder habitual spontaneous abortion pregnancy loss, recurrent, 4 pregnancy loss, recurrent, susceptibility

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ANXIETY DISORDERS RECURRENT PREGNANCY LOSS

Contacts and locations

Locations

242 Hospital Affiliated to Shenyang Medical College

Shenyang, Liaoning, 110000, China
Central Hospital Affiliated to Shenyang Medical College

Shenyang, Liaoning, China
Shenyang Jinghua Hospital

Shenyang, Liaoning, China, China
The Second Affiliated Hospital of Shenyang Medical College

Shenyang, Liaoning, 110001, China

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