GENERALIZED ANXIETY DISORDER

This phase 3 study tests whether an oral medication called MM120 can reduce anxiety symptoms in adults with generalized anxiety disorder (GAD). About 250 participants will receive either MM120 or a placebo for 12 weeks, followed by a 40-week period where everyone can receive MM12…

This study compares two family-based behavioral treatments delivered via telehealth for children aged 7-13 with anxiety or obsessive-compulsive disorder (OCD). The goal is to see if these lower-intensity therapies can reduce symptoms as effectively as standard care. About 100 chi…

This study is testing a 12-week group therapy program for adults with generalized anxiety disorder who have trouble dealing with uncertainty. The program uses cognitive-behavioral techniques to help participants manage worry and anxiety. About 12 to 20 people will take part, and …

This study looks at whether unlicensed professionals can provide cognitive behavioral therapy (CBT) to people with conditions like anxiety, depression, OCD, and PTSD. About 250 participants will receive therapy at Massachusetts General Hospital. The goal is to see if their mental…

This study tests an oral medication called MM120 against a placebo in 214 adults with generalized anxiety disorder. The first 12 weeks are double-blind (neither you nor the doctor knows which group you're in), followed by a 40-week period where everyone can receive MM120. The mai…

This study compares two internet-based cognitive behavioral therapy programs for adults with generalized anxiety disorder. About 400 participants will receive one of two 10-week online treatments targeting either intolerance of uncertainty or negative beliefs about worry. The goa…

This study tests a new medication called CYB004 for people with generalized anxiety disorder (GAD). The goal is to see if it safely reduces anxiety symptoms. About 36 adults with moderate to severe GAD will take either CYB004 or an active control. Researchers will measure anxiety…

This study looked at whether adding physical exercise to cognitive behavioral therapy (CBT) helps older adults with generalized anxiety disorder more than CBT alone. About 53 adults aged 60+ with a primary diagnosis of GAD took part. The goal was to see if the combination leads t…

This study looks at whether it's possible to compare a general therapy approach (transdiagnostic) with a specific one (diagnosis-specific) for people with anxiety disorders like panic disorder or social anxiety. Researchers want to see if they can recruit enough participants, kee…