Sound waves to soothe anxiety? new trial targets the Brain's fear center

NCT ID NCT04557891

First seen Feb 05, 2026 · Last updated Apr 28, 2026 · Updated 12 times

Summary

This study tests whether gentle ultrasound waves aimed at a deep brain area (the amygdala) can reduce anxiety in people with generalized anxiety disorder who haven't gotten better with standard medications. About 48 adults will receive either real or fake ultrasound treatments over four sessions. Researchers will track anxiety levels using standard questionnaires to see if the approach is safe and helpful.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Massachusetts General Hospital

    RECRUITING

    Boston, Massachusetts, 02129, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Medical University of South Carolina

    RECRUITING

    Charleston, South Carolina, 29425, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of California, Los Angeles

    RECRUITING

    Los Angeles, California, 90095, United States

    Contact Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

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