Which sedative is safer and more satisfying for moms during C-Section?

NCT ID NCT07651956

Not yet recruiting Symptom relief Sponsor: Icahn School of Medicine at Mount Sinai Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 29, 2026 · Updated 2 times

Summary

This trial tests two sedatives—remimazolam and dexmedetomidine—to see which better relieves anxiety while keeping pregnant women comfortable and safe during spinal anesthesia placement for scheduled C-sections. The study includes 150 women at full term and measures success by patient satisfaction, memory of the birth, stable vital signs, and willingness to use the medication again. Results may help guide sedation choices in obstetric care.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Remimazolam and dexmedetomidine
What this could lead to: If one drug works better, it could become a preferred option for reducing anxiety during C-section while keeping mothers alert and safe.
What could go wrong: This is a small, early-phase comparison; results may not apply to all patients, and both drugs carry risks like low blood pressure or breathing changes.

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Conditions

The condition(s) this trial relates to.

anxiety anxiety disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ANXIETY PREGNANT PEOPLE

Contacts and locations

Locations

Icahn School of Medicine at Mount Sinai

New York, New York, 10029, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.