Brain study aims to untangle depression and anxiety by tracking how we learn from wins and losses
NCT ID NCT05384158
First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This study looks at how people with depressed mood, loss of interest, or anxiety respond to rewards and losses. Participants will play computer learning games and may have brain scans. The goal is to understand whether these responses are unique or overlapping, which could improve future treatments.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this study could help identify distinct brain patterns linked to depression and anxiety, pointing toward more personalized mental health treatments.
What could go wrong
This is an early observational study, not a treatment trial. It may not lead to direct clinical changes, and results may not apply to everyone with these symptoms.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Fralin Biomedical Research Institute at Virginia Tech Carilion
RECRUITINGRoanoke, Virginia, 24014, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••