Gene test could help teens get the right antidepressant dose faster
NCT ID NCT06853587
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether using a genetic test to guide antidepressant dosing helps teens aged 12-17 with anxiety or depression. About 452 teens will be randomly assigned to either gene-guided dosing or standard dosing. The goal is to see if the genetic approach leads to more remissions and fewer side effects over 12 weeks.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Selective serotonin reuptake inhibitor (SSRI) antidepressant
- What this could lead to
- If successful, this could show that using a simple genetic test helps teens find the right antidepressant dose faster, with fewer side effects.
- What could go wrong
- This is a relatively small, early-stage study. The genetic test may not improve outcomes over standard care, and results may not apply to all teens.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University of Calgary
RECRUITINGCalgary, Alberta, T2N 4N1, Canada
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