Gut-Brain connection in IBS: scientists hunt for clues to anxiety and depression

NCT ID NCT07646834

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study investigates how the gut and brain communicate in people with Irritable Bowel Syndrome (IBS) who also experience anxiety or depression. Researchers will compare 100 IBS patients with anxiety or depression to 100 healthy volunteers using brain scans, stool samples, and blood tests. No treatments are given; the goal is to find biological markers that could improve diagnosis and future care.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could identify biological markers that help diagnose or guide future treatments for IBS with anxiety and depression.

What could go wrong

This is an observational study, not a treatment trial. It may not lead directly to new therapies, and results may not apply to all IBS patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

anxiety anxiety disorder Depression depressive disorder irritable bowel syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Tangdu Hospital, Air Force Medical University

    RECRUITING

    Xi'an, Shaanxi, 710038, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••