CELIAC DISEASE

This study tests an experimental drug called FB102 in 100 adults with celiac disease who already follow a strict gluten-free diet. Participants will receive either the drug or a placebo and then undergo a controlled gluten challenge to see if the drug can reduce intestinal damage…

This study tests a new drug called DONQ52 in people with active celiac disease who still have intestinal damage and symptoms even after following a gluten-free diet for at least a year. The goal is to see if the drug can heal the small intestine and reduce symptoms like belly pai…

This study collects images and videos from routine capsule endoscopy procedures to train an artificial intelligence system. The goal is to help doctors detect bowel diseases like Crohn's, celiac disease, and tumors more accurately and quickly. Up to 10,000 participants will contr…

This study is developing an artificial intelligence (AI) system to detect damage in the small bowel caused by celiac disease and similar conditions. Researchers will train the AI using past endoscopy images and then test it in a new group of 380 adult patients. The goal is to see…

This early-stage study tests a single dose of HB-2121 in 20 adults with suspected celiac disease to see if it's safe and how it works in the small intestine. Participants take the drug before a standard scope procedure and are followed for 30 days. The goal is to develop a better…

This study tests whether a mobile app, supported by a nurse, can improve quality of life for adults newly diagnosed with celiac disease. Sixty participants will either use the app for six months or receive standard education. The goal is to see if the app helps with symptoms, emo…

This study tests if a special toothpaste and mousse can reduce tooth sensitivity and enamel damage in adults with celiac disease. Forty participants will either use only the toothpaste or add a nightly mousse for six months. The goal is to see if the mousse provides extra relief …

This study tests a new drug called ZED1227 for adults with celiac disease who still have symptoms like stomach pain and bloating even after following a gluten-free diet for at least a year. About 356 participants will receive either the drug or a placebo to see if it improves the…

This early-stage trial tests a new medicine called VTP-1000 in 45 adults with celiac disease. The main goal is to see if it is safe and how the body handles it. Some participants will also eat gluten in a controlled way to see if the drug helps reduce reactions. This study is a f…

This study aims to uncover genetic, immune, and gut bacteria differences between various forms of celiac disease and a related skin condition called dermatitis herpetiformis. Researchers will follow 3,500 adults with these conditions, plus their friends or relatives, to find mark…

This study looks at how the immune system of children with celiac disease responds to very small amounts of gluten, like what might happen with accidental exposure. About 51 kids on a strict gluten-free diet will take either a placebo or a low or high dose of gluten for three day…

This study is testing whether it's practical to screen thousands of children for early signs of type 1 diabetes and celiac disease during their regular doctor visits. Researchers will enroll up to 33,000 children from birth to age 6 and follow them for about 5 years. The goal is …

This study follows 500 infants who have a close family member with celiac disease and are under 6 months old. Researchers will track their genes, diet, and gut bacteria over time to learn what triggers the disease. The goal is to find ways to prevent or detect celiac disease earl…

This study aims to find out how common non-celiac wheat sensitivity (NCWS) and other gut issues like irritable bowel syndrome (IBS) are among relatives of people with celiac disease. Researchers will ask 600 adult relatives to follow a wheat-free diet for 6 weeks and report their…

This study collects tissue and blood samples from 300 people with autoimmune diseases like Crohn's, multiple sclerosis, and celiac disease. Researchers will look for T cells that are active in inflamed tissues to find their targets. The goal is to discover new targets for future …

This study looks at how celiac disease damages the gut and how it heals. Researchers will study 220 adults, including those on a gluten-free diet, those with active symptoms, and healthy controls. The goal is to better understand the disease and improve care for patients.

This study is collecting tissue samples from 300 people to improve how doctors diagnose small-bowel diseases like celiac disease. Researchers will use advanced tools like AI and genetic analysis to create more accurate reference values and diagnostic methods. The goal is to bette…

This study aims to understand why the immune system attacks the gut in conditions like celiac disease, autoimmune enteropathy, and inflammatory bowel disease. Researchers will analyze immune cells from 200 adult participants to uncover the mechanisms behind these diseases. The go…

This study is collecting health information from up to 10,000 people with conditions like Long COVID, ME/CFS, and autoimmune diseases. Participants use a smartphone app to share symptoms, health history, and wearable data. The goal is to better understand these illnesses and help…

This study looks at how people with celiac disease react to gluten in liquid form (a shake) versus solid form (a cookie). Thirty adults on a gluten-free diet will take part, giving blood samples to measure immune markers like IL-2. The goal is to see if one form triggers a strong…