CELIAC DISEASE

This study tested a new medicine called TAK-101 in 102 adults with celiac disease who already follow a gluten-free diet. The goal was to see if TAK-101 could reduce immune reactions and symptoms if they accidentally eat gluten. Participants received two doses of TAK-101 or a plac…

This study tested whether the drug ritlecitinib can prevent intestinal damage and symptoms caused by gluten in people with celiac disease who are already on a gluten-free diet. 62 adults with inactive celiac disease took either the drug or a placebo along with a small amount of g…

This study tested a new medicine called TPM502 in 28 adults with celiac disease. Participants received two infusions of TPM502 or a placebo, two weeks apart. The goal was to see if the treatment is safe and if it can help the body become more tolerant to gluten, potentially reduc…

This study looked at whether a probiotic called LP-LDL can help lower cholesterol in people with celiac disease. Researchers gave the probiotic to 50 adults with celiac disease and high cholesterol to see if it improved their cholesterol levels and body weight. The goal was to fi…

This study tested an experimental drug called PRV-015 in 388 adults with celiac disease whose symptoms (like belly pain, bloating, and diarrhea) continue despite following a strict gluten-free diet. Participants received either the drug or a placebo for 24 weeks to see if it coul…

This study tested an experimental drug called KAN-101 in 55 adults with celiac disease who had been on a gluten-free diet for at least a year. The goal was to see if the drug could reduce damage to the small intestine caused by a two-week gluten challenge. Results suggested KAN-1…

This early-stage study tested the safety of a single dose of HB-2121, a potential diagnostic for celiac disease, in 18 healthy adults and people with celiac disease. Researchers monitored side effects and how the drug moved through the body over 30 days. The goal was to see if HB…

This study looked at whether reducing FODMAPs—certain carbohydrates found in many foods—can ease persistent stomach symptoms in people with celiac disease who already follow a strict gluten-free diet. Researchers surveyed and then randomly assigned 80 adults to test a low FODMAP …

This study looked at whether a specific type of oat called Saul is safe for adults with celiac disease who are already in remission. Forty participants ate 50 grams of gluten-free Saul oat flakes daily for two weeks. Researchers tracked symptoms and blood markers to see if the oa…

This study involved 33 adults with celiac disease who followed a strict gluten-free diet. Researchers gave them small amounts of different gluten types (wheat, barley, and hydrolyzed barley) in separate one-day challenges to see how their immune systems responded. The goal was to…

This study looked at whether taking a bowel-cleansing solution before a small bowel capsule endoscopy helps doctors see the intestine better and find problems more often. 230 adults referred for the procedure were randomly assigned to receive either a split dose, a single morning…