Can a pill shield celiac patients from accidental gluten?

NCT ID NCT05636293

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tested whether the drug ritlecitinib could prevent intestinal damage and symptoms when people with celiac disease ate gluten. 62 adults with well-controlled celiac disease (on a gluten-free diet) took either the drug or a placebo along with a daily gluten challenge. The goal was to see if the drug could block the immune reaction and protect the gut lining.

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Conditions

The condition(s) this trial relates to.

celiac disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States