Scientists probe immune System's role in chronic disease

NCT ID NCT01143480

Recruiting now Knowledge-focused Sponsor: National Institute of Environmental Health Sciences (NIEHS) Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Aug 07, 2026 · Updated 6 times

Summary

This study looks at how the body's innate immune system responds to certain environmental exposures by measuring inflammation markers in blood. Researchers will collect blood samples from up to 725 healthy volunteers aged 18-45 to analyze how specific genes and proteins react. The goal is to better understand how these responses might contribute to chronic illnesses like asthma, atherosclerosis, and cancer.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this study could help explain how environmental factors trigger inflammation that may lead to chronic diseases.
What could go wrong: This is an observational study in healthy volunteers, not a treatment trial. It may not directly lead to new therapies or apply to people with existing conditions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

abdominal obesity-metabolic syndrome asthma atherosclerosis cancer Insulin Resistance metabolic syndrome X neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ASTHMA ATHEROSCLEROSIS CANCER INSULIN RESISTANCE METABOLIC SYNDROME

Contacts and locations

Locations

NIEHS Clinical Research Unit (CRU)
RECRUITING

Research Triangle Park, North Carolina, 27709, United States

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