National Institute Of Environmental Health Sciences (niehs)

This study is testing an oral drug called H01 (hymecromone) in adults with progressive interstitial lung disease, a condition that causes scarring and thickening of lung tissue. The main goal is to see if H01 can reduce levels of a substance called hyaluronan in the blood, which …

This study aims to understand how everyday environmental factors like pollution, diet, and stress contribute to disease and inflammation. Researchers will collect various samples—such as blood, saliva, urine, and even household dust—from up to 2,000 healthy adults. The goal is to…

This study aims to understand if certain environmental factors, like infections, chemicals, or stressful events, might trigger a rare autoimmune disease that weakens muscles and can affect the lungs. Researchers will compare the past exposures of 580 people—including those with t…

This study aims to understand how a person's genes affect how their immune cells respond to potential threats. Researchers will collect blood from healthy volunteers to grow immune cells in a lab and test their reactions. The goal is to learn if certain genetic patterns make peop…

This study aims to better understand the causes and effects of rare inflammatory muscle diseases like dermatomyositis and polymyositis. Researchers will observe up to 1,200 participants, including both patients and healthy volunteers, over time. The goal is to learn how these dis…

This study aims to understand if girls with higher body weight start puberty earlier than girls with normal weight. Researchers will use breast ultrasounds, blood tests, and other exams on 150 healthy girls aged 8-14 to get a clearer picture. The goal is to gather better informat…

This study aims to understand how environmental factors like bacteria and household dust affect asthma over time. Researchers will follow 400 adults with moderate-to-severe asthma for five years, collecting samples like blood, saliva, stool, and dust. The goal is to gather inform…

This study aims to understand how our environment and our genes work together to influence our risk for common diseases like diabetes, heart disease, and asthma. It will enroll 25,000 adults to collect detailed health, lifestyle, and genetic information to build a research resour…

This study aims to understand how reproductive disorders like infertility, delayed puberty, or early puberty are inherited. Researchers will recruit 850 people with these conditions, along with their family members, to analyze their genes and medical histories. The goal is to ide…

This study aims to understand the long-term effects of the COVID-19 pandemic on women from minority communities in North Carolina. Researchers are recruiting 700 participants to complete surveys and may collect samples like blood or saliva. The goal is to gather information to he…

This study aims to understand how environmental factors like pollution, chemicals, diet, and lifestyle might affect reproductive health and hormone-related disorders. It will observe 300 participants, aged 8 and older, who have conditions like early or late puberty, infertility, …

This study aims to understand how the body's white blood cells sense and respond to signals that trigger inflammation. Researchers will collect blood from healthy volunteers and test how different immune cells react to various substances in the lab. The goal is to map the interna…

This study aims to learn how girls' menstrual cycles develop and become regular in the years after their first period. Researchers are observing 400 girls and young women, including some at risk for a hormone condition called PCOS, by tracking their cycles and collecting urine an…