Scientists hunt for genes behind puberty problems

NCT ID NCT01500447

Recruiting now Knowledge-focused Sponsor: National Institute of Environmental Health Sciences (NIEHS) Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 29, 2026 · Updated 3 times

Summary

This study aims to understand how reproductive disorders, such as delayed or early puberty, are inherited. Researchers will collect blood samples and medical histories from 850 people with these conditions and their family members. No treatment is provided; the goal is to identify genetic variants linked to these disorders.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this study could help identify genes linked to inherited reproductive disorders, paving the way for future treatments or diagnostic tests.
What could go wrong: This is an observational study, not a treatment trial. It may not directly benefit participants, and finding meaningful genetic links is uncertain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

amenorrhea hereditary disease hypogonadism hypogonadotropic hypogonadism 7 with or without anosmia infertility disorder Kallmann syndrome precocious puberty Puberty, Delayed

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AMENORRHEA GENETIC DISORDER HYPOGONADISM INFERTILITY

Contacts and locations

Locations

NIEHS Clinical Research Unit (CRU)
RECRUITING

Research Triangle Park, North Carolina, 27713, United States
National Institutes of Health Clinical Center
RECRUITING

Bethesda, Maryland, 20892, United States

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