Fish oil capsules could ease rare muscle disease

NCT ID NCT07111065

Recruiting now Disease control Sponsor: National Institute of Environmental Health Sciences (NIEHS) Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Aug 14, 2026 · Updated 34 times

Summary

This study tests whether omega-3 fatty acid supplements from fish oil, combined with a healthy diet, can reduce disease activity in adults with dermatomyositis, a rare autoimmune disease causing muscle weakness and skin rashes. About 300 participants will take either fish oil capsules or a placebo for 6 months, with regular check-ins and dietary coaching. The goal is to see if this simple supplement can improve symptoms and quality of life.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: omega-3 fatty acids from fish oil
What this could lead to: If it works, this could point toward a simple dietary supplement to help manage dermatomyositis symptoms and reduce disease activity.
What could go wrong: This is an early phase 2 trial with only 300 participants, so results may not apply to everyone. The supplement may show no benefit over placebo, and dietary changes can be hard to maintain.

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Conditions

The condition(s) this trial relates to.

dermatomyositis juvenile dermatomyositis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DERMATOMYOSITIS (DM) JUVENILE DERMATOMYOSITIS (JDM)

Contacts and locations

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Study contacts

Contact

Email: •••••@•••••

Locations

National Institutes of Health Clinical Center
RECRUITING

Bethesda, Maryland, 20892, United States

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