New drug targets immune diseases in early trial

NCT ID NCT06371417

Recruiting now Disease control Sponsor: Chugai Pharmaceutical Source: ClinicalTrials.gov ↗

First seen Apr 07, 2026 · Last updated May 15, 2026 · Updated 5 times

Summary

This early-stage study tests a new drug called RAY121 in people with six different immune system diseases, including antiphospholipid syndrome and bullous pemphigoid. The main goal is to check safety and how the body processes the drug. About 144 adults will take part to see if the drug can help control these conditions.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

"SHATHD" EAD Sofia
NOT_YET_RECRUITING

Sofia, Sofia City Province, 1756, Bulgaria
AKH - Medizinische Universitaet Wien, Abteilung fuer Klinische Pharmakologie
NOT_YET_RECRUITING

Vienna, 1090, Austria
AP-HP Hôpital Universitaire Pitié Salpêtrière
RECRUITING

Paris, Île-de-France Region, 75013, France
Amarillo Center for Clinical Research
ACTIVE_NOT_RECRUITING

Amarillo, Texas, 79124, United States
Austin Neuromuscular Center
RECRUITING

Austin, Texas, 78759, United States
Box Hill Hospital
RECRUITING

Melbourne, Victoria, 3128, Australia
Campbelltown Public Hospital
RECRUITING

Sydney, New South Wales, 2560, Australia
Centre de Rhumatologie de l'Est du Quebec
RECRUITING

Rimouski, Quebec, G5L 8W1, Canada
Centro Clinico Academico Braga
NOT_YET_RECRUITING

Braga, Braga District, 471-243, Portugal
Centro Hospitalar de Vila Nova de Gaia/Espinho, E.P.E.
NOT_YET_RECRUITING

Vila Nova de Gaia, Porto District, 4434-502, Portugal
Centrul Medical Monza SRL
RECRUITING

Bucharest, Bucharest Municipality, 400015, Romania
Clinica Universidad de Navarra
NOT_YET_RECRUITING

Pamplona, Community of Madrid & Navarre, 28027, Spain
Clinical Hospital Center "Sestre Milosrdnice"
NOT_YET_RECRUITING

Zagreb, City of Zagreb, 10000, Croatia
DIEX Recherche Sherbrooke Inc.
RECRUITING

Sherbrooke, Quebec, J1L 0H8, Canada
Diagnostic Consultation Center CONVEX EOOD
NOT_YET_RECRUITING

Sofia, Sofia City Province, 1202, Bulgaria
Dr. Abdurrahman Yurtaslan Oncology Teaching and Research Hospital
NOT_YET_RECRUITING

Ankara, Ankara, 06200, Turkey (Türkiye)
Hamamatsu University Hospital
RECRUITING

Hamamatsu, Shizuoka, 431-3192, Japan
Hokkaido University Hospital
RECRUITING

Sapporo, Hokkaido, 060-0808, Japan
Hopital Lapeyronie,Service d'Immuno Rhumatologie
NOT_YET_RECRUITING

Montpellier, Occitanie, 34295, France
Hospital Universitari Vall d'Hebron, Internal Medicine Dept.
NOT_YET_RECRUITING

Barcelona, Province of Barcelona and Catalonia, 08035, Spain
Hospital Universitari i Politecnic La Fe
NOT_YET_RECRUITING

Valencia, Valencia, 46026, Spain
Hospital Universitario 12 de October
NOT_YET_RECRUITING

Madrid, Madrid, 28041, Spain
Hospital Universitario Ramon y Cajal, Servicio de Reumatologia
NOT_YET_RECRUITING

Madrid, Madrid, 28034, Spain
Hospital Universitario Reina Sofia
NOT_YET_RECRUITING

Córdoba, Province Of Córdoba, 14004, Spain
Hospital Universitario Virgen del Rocio
RECRUITING

Seville, Province Of Seville, 41013, Spain
Hospital for Special Surgery
ACTIVE_NOT_RECRUITING

New York, New York, 10021, United States
IRCCS Istituto Scientifico Romagnolo Per Lo Studio Dei Tumori "Dino Amadori" - IRST
NOT_YET_RECRUITING

Meldola, Forlì-Cesena Province, 47014, Italy
Institute Reumatologii I'm. Eleonory Reicher
RECRUITING

Warsaw, Masovian Voivodeship, 02-637, Poland
Istanbul University Istanbul Medical Faculty
NOT_YET_RECRUITING

Istanbul, Istanbul, 34093, Turkey (Türkiye)
Istituto Clinico Humanitas
NOT_YET_RECRUITING

Milan, Milan Province, 20089, Italy
Johns Hopkins University
NOT_YET_RECRUITING

Baltimore, Maryland, 21224, United States
Kindai University Hospital
NOT_YET_RECRUITING

Sayama, Osaka, 589-8511, Japan
National Center of Neurology and Psychiatry
RECRUITING

Kodaira, Tokyo, 187-8551, Japan
National Taiwan University Hospital
RECRUITING

Taipei, 100229, Taiwan
Nerve and Muscle Center of Texas
NOT_YET_RECRUITING

Houston, Texas, 77030, United States
Northwell Health, LLC PRIME
ACTIVE_NOT_RECRUITING

Lake Success, New York, 11042, United States
Ohio State University
WITHDRAWN

Columbus, Ohio, 43203, United States
Okayama University Hospital
RECRUITING

Okayama, 700-8558, Japan
Oncology Institute Prof. Dr. Ion Chiricuta I.O.C.N.
RECRUITING

Cluj-Napoca, Cluj, 11658, Romania
Oregon Health & Science University
RECRUITING

Portland, Oregon, 97239, United States
Osaka University Hospital
RECRUITING

Suita, Osaka, 565-0871, Japan
Ospedale San Giovanni Bosco
NOT_YET_RECRUITING

Torino, Turin Province, 10154, Italy
Royal Prince Alfred Hospital
RECRUITING

Camperdown, New South Wales, 2050, Australia
Sanatorium Profesora Arenbergera
NOT_YET_RECRUITING

Prague, Prague, 11000, Czechia
Semmelweis Egyetem
NOT_YET_RECRUITING

Budapest, 1083, Hungary
Sorlandet sykehus Kristiansand
NOT_YET_RECRUITING

Kristiansand, Agder County, 4604, Norway
Specialty Hospital Medico
NOT_YET_RECRUITING

Rijeka, Primorje-Gorski Kotar County, 51000, Croatia
Stavanger Universitetssjukehus
NOT_YET_RECRUITING

Stavanger, Rogaland County, 4011, Norway
Szegedi Tudomanyegyetem Szent-Gyorgyi Albert Klinikai Kozpont
NOT_YET_RECRUITING

Szeged, Csongrád-Csanád County, 6720, Hungary
Taichung Veterans General Hospital
NOT_YET_RECRUITING

Taipei, 407219, Taiwan
The Alfred Hospital
RECRUITING

Melbourne, Victoria, 3004, Australia
The Royal Institution for the Advancement of Learning/McGill University
RECRUITING

Montreal, Quebec, H3A 0G4, Canada
Toho University Omori Medical Center
RECRUITING

Ōta-ku, Tokyo, 143-8540, Japan
Tohoku University Hospital
RECRUITING

Sendai, Miyagi, 980-8574, Japan
UMC Utrecht
NOT_YET_RECRUITING

Utrecht, Utrecht Province, 3584 CX, Netherlands
UMHAT "Prof. Dr. St. Kirkovich", AD
NOT_YET_RECRUITING

Stara Zagora, Stara Zagora Province, 6003, Bulgaria
Universitaetsklinikum Carl Gustav Carus TU Dresden, Klinik und Poliklinik f. Dermatologie
NOT_YET_RECRUITING

Sachsen, Bundesländer, 1307, Germany
Universitaetsklinikum Erlangen
NOT_YET_RECRUITING

Erlangen, Bavaria, 91054, Germany
Universitaetsklinikum Schleswig Holstein - Campus Luebeck, Klinik f Dermatologie, Allergologie u Venerologie
NOT_YET_RECRUITING

Lübeck, Schleswig-Holstein, 23538, Germany
Universitaetsklinikum Tuebingen
NOT_YET_RECRUITING

Tübingen, Baden-Wurttemberg, 72076, Germany
Universitaetsmedizin Goettingen
NOT_YET_RECRUITING

Göttingen, Göttingen District, 3075, Germany
University Medical Centre Groningen UMCG
NOT_YET_RECRUITING

Groningen, Groningen Province, 9713 GZ, Netherlands
University hospital centre Zagreb
NOT_YET_RECRUITING

Zagreb, City of Zagreb, 10000, Croatia
University of Alberta Hospital - Department of Anesthesiology and Pain Medicine
RECRUITING

Edmonton, Alberta, T6G 2B7, Canada
University of Alberta Hospital - Dermatology
RECRUITING

Edmonton, Alberta, T6G 2G3, Canada
University of California-Irvine
RECRUITING

Orange, California, 92868, United States
University of Pennsylvania, Perelman Center for Advanced Medicine
RECRUITING

Philadelphia, Pennsylvania, 19104, United States
Universtity of North Carolina at Chapel Hill
NOT_YET_RECRUITING

Chapel Hill, North Carolina, 27599, United States
Westmead Hospital
RECRUITING

Sydney, New South Wales, 2145, Australia

Conditions

Explore the condition pages connected to this study.

ANTIPHOSPHOLIPID SYNDROME (APS) BEHÇET'S SYNDROME (BS) BEHÇET'S SYNDROME (BS) BULLOUS PEMPHIGOID (BP) DERMATOMYOSITIS (DM) IMMUNE THROMBOCYTOPENIA (ITP) IMMUNE-MEDIATED NECROTIZING MYOPATHY (IMNM)