Can a gut bacteria transplant help when steroids fail for a bleeding disorder?

NCT ID NCT07733037

Ongoing Disease control Sponsor: Peking University People's Hospital Source: ClinicalTrials.gov ↗

First seen Jul 29, 2026 · Last updated Jul 30, 2026 · Updated 1 time

Summary

This phase 2 trial tests whether fecal microbiota transplantation (FMT) — transferring gut bacteria from a healthy donor — can help adults with chronic immune thrombocytopenia (ITP) whose disease has not responded to or has relapsed after steroid treatment. Participants will receive either FMT capsules or placebo capsules for six days. The study aims to see if FMT can safely raise platelet counts and improve disease control.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: fecal microbiota transplantation (FMT) given as capsules
What this could lead to: If it works, this could offer a new treatment option for people with immune thrombocytopenia who do not respond to steroids.
What could go wrong: This is an early phase 2 trial with only 42 participants, so results may not apply broadly. FMT carries risks of infection or digestive side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Purpura, Thrombocytopenic, Idiopathic thrombocytopenia due to immune destruction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

IMMUNE THROMBOCYTOPENIA (ITP)

Contacts and locations

Locations

Peking University People's Hospital

Beijing, China

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