National Institute Of Environmental Health Sciences (niehs)

This study looked at whether a chemical called TGF-Beta, found in higher levels in the lungs of people with asthma, makes them more likely to get severe infections from RSV, a common respiratory virus. Researchers collected lung cells from 113 healthy adults and mild asthmatics u…

This study looked at families where one sibling has a rheumatic disease (like rheumatoid arthritis or lupus) and the other does not. Researchers compared their blood cells, genes, and environmental exposures to find clues about why one got sick. Over 1,000 people took part, inclu…

This study aimed to improve how scientists measure people's contact with chemicals in common household and personal care products. Eleven healthy women aged 35-74 who used at least 15 products daily took part. Researchers compared surveys, air samplers, dust samples, and urine te…

This study looked at how certain genes might change the way lung cells (macrophages) work when exposed to environmental pollutants. Researchers collected blood and lung samples from 20 healthy adults to compare cell function between people with and without specific genetic variat…

This study looked at people with low or no levels of a hormone called GnRH, which is important for starting puberty and having children. Researchers measured hormone patterns and did imaging and smell tests to learn more about these conditions. The goal was to better understand t…

This study looked at why Black and white workers have different sleep patterns. Researchers held focus groups with 263 employed adults to discuss work, sleep, and health. The goal was to uncover reasons behind racial sleep differences, not to test a treatment.

This study follows nearly 90,000 farmers and their spouses to track long-term health effects from pesticides and farm work. Researchers confirm self-reported diseases like asthma and Parkinson's by reviewing medical records and collecting cheek swabs. The goal is to understand ho…

This study looked at why some military personnel develop myositis, a rare disease where the immune system attacks muscle tissue, causing weakness and pain. Researchers compared 37 people—some with myositis and some healthy—using questionnaires and blood samples to find possible e…

This study looked at how small differences in certain genes affect the way blood cells respond to environmental exposures. Researchers collected blood samples from 178 healthy adults aged 18 to 45 to measure gene activity and protein binding. The goal was to better understand why…

This study looked at how smoking changes immune cells and whether those changes make COVID-19 worse. Researchers followed 132 healthy smokers and non-smokers aged 30-55 for up to 6 months, taking blood, saliva, and nasal samples to track infections and immune responses. The goal …

This study looked at how diet and exercise changes affect hormones and menstrual cycles in healthy women aged 18-28. Researchers wanted to better understand a condition called functional hypothalamic amenorrhea, where periods stop temporarily due to the brain not directing the re…

This study looked at what causes autoimmune diseases that affect muscles and connective tissues, like myositis. Researchers studied 719 people, including patients, their relatives, and healthy volunteers, to find genetic and environmental risk factors. Participants gave blood sam…

This study looked at how small changes in the COX-2 gene affect the balance of immune cells that can lead to allergies or asthma. Researchers collected blood and urine samples from 117 adults to analyze these gene variations. No treatments were given; the goal was simply to under…

This study looked at how certain gene variations affect the health of blood vessels in 178 healthy adults. Participants had an ultrasound and a short-acting medication to measure blood flow. The goal was to learn more about genetic risks for heart disease, not to provide treatmen…

This study created a collection of biological and environmental samples from over 5,000 healthy adults. The samples—including blood, urine, saliva, and household dust—were used to develop and validate new laboratory tests and ensure quality control. No treatments or interventions…

This study aimed to find out how many healthy adults in central North Carolina had been exposed to COVID-19 by testing their blood for antibodies over one year. Participants were 643 adults aged 18 and older who did not have COVID-19 at the start. They provided blood samples and …

This study looked at whether taking vitamin D supplements can improve menstrual cycle health in women aged 19-40 with regular periods. 57 women took either vitamin D or a placebo for about 3 months. Researchers measured hormone levels to see if vitamin D affects ovulation and fer…