National Institute Of Environmental Health Sciences (niehs)
Clinical trials sponsored by National Institute Of Environmental Health Sciences (niehs), explained in plain language.
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Scientists track chemicals in your home
Knowledge-focused CompletedThis study aimed to test and improve methods for measuring people's exposure to chemicals found in common household and personal care products. It involved 11 healthy women who used many products daily. Researchers collected air, dust, urine, and blood samples while participants …
Sponsor: National Institute of Environmental Health Sciences (NIEHS) • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:47 UTC
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Why one twin gets sick: NIH hunts clues in families
Knowledge-focused CompletedThis study aimed to understand why some people develop autoimmune rheumatic diseases like rheumatoid arthritis or lupus while their genetically similar siblings do not. Researchers enrolled over 1,000 participants, including sibling pairs where one was affected and one was health…
Sponsor: National Institute of Environmental Health Sciences (NIEHS) • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:43 UTC
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Year-Long study maps hidden COVID spread through blood tests
Knowledge-focused CompletedThis study aimed to understand how many adults in North Carolina developed antibodies to the COVID-19 virus over time. Researchers followed 643 healthy adults for one year, drawing their blood five times to check for antibodies and having them complete weekly symptom surveys. The…
Sponsor: National Institute of Environmental Health Sciences (NIEHS) • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:43 UTC
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Scientists probe why some women lose their periods
Knowledge-focused CompletedThis study aimed to understand why some women temporarily stop having periods, a condition called functional hypothalamic amenorrhea. Researchers observed 38 healthy women aged 18-28 to see how controlled changes in their diet and exercise affected their menstrual cycles and horm…
Phase: NA • Sponsor: National Institute of Environmental Health Sciences (NIEHS) • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:41 UTC
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Can a vitamin pill improve Women's fertility signals?
Knowledge-focused CompletedThis study aimed to understand if taking vitamin D supplements affects hormones related to menstrual cycles and ovulation. Researchers enrolled 57 women aged 19-40 with regular cycles. Women with low vitamin D levels received a high-dose weekly supplement for about 90 days, while…
Phase: PHASE2 • Sponsor: National Institute of Environmental Health Sciences (NIEHS) • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:12 UTC
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Study probes why black professionals get worse sleep than white peers
Knowledge-focused CompletedThis study aimed to understand why Black professionals tend to have shorter, poorer quality sleep than their White counterparts, which can lead to serious health problems. Researchers held focus groups with over 260 employed Black and White adults in North Carolina and Washington…
Sponsor: National Institute of Environmental Health Sciences (NIEHS) • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:12 UTC
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Scientists probe why smokers face deadlier COVID-19
Knowledge-focused CompletedThis study aimed to understand why smokers might get sicker from COVID-19. Researchers followed 132 healthy adults, both smokers and non-smokers, for up to 6 months. They collected blood and other samples to compare immune system differences before and after a COVID-19 infection.
Sponsor: National Institute of Environmental Health Sciences (NIEHS) • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:12 UTC
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Scientists probe genetic link to lung inflammation
Knowledge-focused CompletedThis study aimed to understand how specific genes affect how lung cells respond to environmental pollutants. Researchers collected lung and blood samples from 20 healthy adults to study cell function in a lab. The goal was to gather basic knowledge about the early steps that migh…
Sponsor: National Institute of Environmental Health Sciences (NIEHS) • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:33 UTC
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Scientists probe Gene's role in allergic reactions
Knowledge-focused CompletedThis study aimed to understand how specific variations in a gene called COX-2 might influence the development of certain immune cells linked to allergic inflammation and asthma. Researchers enrolled 117 adults from a registry to compare blood and urine samples from people with di…
Sponsor: National Institute of Environmental Health Sciences (NIEHS) • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:30 UTC
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Military mystery: What's causing Soldiers' muscle disease?
Knowledge-focused CompletedThis study aimed to understand why some military personnel develop myositis, a rare autoimmune disease that attacks muscles, while others do not. Researchers compared service members with myositis to healthy service members, looking for common environmental exposures during milit…
Sponsor: National Institute of Environmental Health Sciences (NIEHS) • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:30 UTC
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Scientists probe genetic links to inflammation and disease
Knowledge-focused CompletedThis study aimed to understand how specific variations in certain genes affect how a person's blood cells respond to stress or damage. Researchers collected blood samples from 178 healthy volunteers and some people with HIV to measure cell reactions in a lab. The goal was to gath…
Sponsor: National Institute of Environmental Health Sciences (NIEHS) • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:39 UTC
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Scientists probe genetic links to heart disease in healthy volunteers
Knowledge-focused CompletedThis study aimed to understand how specific gene variations might affect blood vessel function, which is important for heart health. Researchers examined 178 healthy adults who carried certain gene patterns to see if these variations were linked to differences in how their blood …
Sponsor: National Institute of Environmental Health Sciences (NIEHS) • Aim: Knowledge-focused
Last updated Mar 24, 2026 12:02 UTC
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Scientists hunt for hidden triggers of crippling muscle diseases
Knowledge-focused CompletedThis study aimed to discover what causes rare autoimmune diseases that attack muscles and connective tissues, like polymyositis and dermatomyositis. Researchers studied 719 people, including patients and their family members, to look for genetic clues and environmental triggers l…
Sponsor: National Institute of Environmental Health Sciences (NIEHS) • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:19 UTC
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Scientists probe why colds hit asthmatics harder
Knowledge-focused CompletedThis study aimed to understand why people with asthma often get sicker from common cold viruses like RSV. Researchers collected lung cells from 113 adults, both with and without mild asthma, to test in the lab. They wanted to see if a specific body chemical (TGF-beta) found more …
Sponsor: National Institute of Environmental Health Sciences (NIEHS) • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:16 UTC
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Thousands donate samples to build a 'Biobank' for future science
Knowledge-focused CompletedThis study created a registry of anonymous biological and environmental samples from adult volunteers. The purpose was to collect materials like blood, urine, and household dust to help scientists develop, test, and improve the accuracy of new laboratory tests for future research…
Sponsor: National Institute of Environmental Health Sciences (NIEHS) • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:15 UTC
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Massive farming health study checks up on 89,000 participants
Knowledge-focused CompletedThis study is following up with about 89,000 farmers and their spouses to better understand the long-term health effects of farming exposures like pesticides. Researchers are checking the accuracy of health problems participants have reported, such as asthma and Parkinson's disea…
Sponsor: National Institute of Environmental Health Sciences (NIEHS) • Aim: Knowledge-focused
Last updated Mar 20, 2026 14:48 UTC
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Scientists probe mystery of missing puberty hormones
Knowledge-focused CompletedThis study aimed to understand a rare condition where the body doesn't produce enough of a key hormone (GnRH) needed to start puberty and support fertility. Researchers studied 111 teenagers and adults with this condition to map their hormone patterns and look for other related h…
Sponsor: National Institute of Environmental Health Sciences (NIEHS) • Aim: Knowledge-focused
Last updated Mar 09, 2026 14:24 UTC