Smoking and COVID-19: new study investigates immune cell changes
NCT ID NCT04403386
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study followed 132 healthy smokers and non-smokers aged 30-55 to see how smoking history affects immune cells and COVID-19 risk. Participants provided blood, saliva, and nasal swab samples over up to six monthly visits. The goal is to understand why smokers may have more severe COVID-19 outcomes.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this could help explain why smokers face higher risks from COVID-19 and guide future prevention strategies.
What could go wrong
This is an observational study, not a treatment trial. It cannot prove cause and effect, and results may not apply to all populations.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for COVID-19 are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
NIEHS Clinical Research Unit (CRU)
Research Triangle Park, North Carolina, 27709, United States