Twin study seeks clues to rheumatic disease mysteries
NCT ID NCT00055055
First seen Jun 24, 2026 · Last updated Jul 01, 2026 · Updated 3 times
Summary
This study looks at families where one sibling has a rheumatic disease (like rheumatoid arthritis or lupus) and the other does not. Researchers compare their blood, genes, and environmental exposures to find clues about why one got sick. Over 1,000 participants are involved, including siblings, parents, and healthy volunteers. The goal is to understand what causes these diseases, not to test a new treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this study could help identify genetic or environmental factors that trigger rheumatic diseases, pointing toward future prevention or treatment strategies.
What could go wrong
This is an observational study, not a treatment trial. It may not find clear differences, and results may not directly lead to new therapies.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for SYSTEMIC SCLEROSIS are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
NIEHS Clinical Research Unit (CRU)
Research Triangle Park, North Carolina, United States
-
National Institutes of Health Clinical Center
Bethesda, Maryland, 20892, United States
-
University of Wisconsin
Madison, Wisconsin, 53792, United States