CANCER

This trial tested a personalized cancer vaccine made from a patient's own tumor cells. It aimed to see if the vaccine could slow tumor growth, improve survival, and trigger an immune response. The study included 63 adults with various solid tumors, but was stopped early.

This study tested a new drug called PLX038 in 14 people with advanced triple-negative breast cancer that had already been treated. The goal was to see if the drug could shrink tumors. The trial was terminated early, so results are limited.

This study tested a new drug called OC-001, given alone or with an immunotherapy drug (Avelumab), in people with advanced cancers that had spread. The goal was to check safety and how the drug moves through the body. The study was stopped early and involved 73 participants with v…

This study tested a combination of two immunotherapy drugs (durvalumab and tremelimumab) in people with advanced rare solid tumors that had not responded to standard treatments. The goal was to see if the drugs could shrink tumors and to check for side effects. The trial was term…

This early-stage study tested whether combining precise radiation to the spine with the immunotherapy drug pembrolizumab is feasible for people with advanced spinal tumors pressing on the spinal cord. Only one person enrolled before the study was stopped early. The goal was to se…

This study aimed to see if adding the drug pembrolizumab to chemotherapy could help control lung cancer that has spread to the brain without causing new symptoms. It was designed for people with untreated, asymptomatic brain metastases and no specific genetic mutations. However, …

This early-stage study tested a new drug called INKmune in people with myelodysplastic syndrome (MDS) or acute myeloid leukemia (AML). The goal was to see if it was safe and to find the best dose. Only 2 people took part before the study was stopped early.

This study tested whether a combination of two drugs (venetoclax and azacitidine) could help people with acute myeloid leukemia (AML) live longer after a stem cell transplant. The trial included adults and teenagers who had a transplant or were planning one. The goal was to see i…

This study looked at whether a structured smoking cessation program, started four weeks before surgery, could reduce complications in smokers undergoing intermediate to high-risk operations. Researchers planned to enroll 251 adults who smoked daily and were scheduled for surgerie…

This study tested an experimental drug called SQ3370 in 53 people with advanced solid tumors that had stopped responding to other treatments. The main goal was to find a safe dose and check for side effects. The study was terminated early, so results are limited.

This study aimed to give children with relapsed or hard-to-treat neuroblastoma a personalized treatment plan. Doctors would analyze the tumor's genes and pick a combination of targeted drugs to attack the specific mutations found. The trial was stopped early, so results are limit…

This study tested a new imaging method called AWSM-PET/CT to see if it can find small cancer spots better than standard PET/CT scans. It involved 11 adults with known or suspected cancer who were already scheduled for a standard scan. The goal was to compare the accuracy of the n…

This study tested a technique called Narrow Band Imaging (NBI) that uses special light to help surgeons see early cancer spots in the mouth that are hard to detect with the naked eye. The goal was to see if NBI could help remove all cancer tissue during surgery. The trial include…

This study tested an online support group for young adults (ages 18-39) who had cancer treatment and were feeling anxious or distressed during the COVID-19 pandemic. The goal was to see if teaching healthy coping skills through a virtual group could improve their mood and confide…

This study tested a morphine gel applied directly to painful mouth sores caused by chemotherapy in children and young adults ages 5 to 25. The goal was to see if the gel could relieve pain better than morphine given through an IV. The study was stopped early, but it aimed to help…

This study tested two educational programs for parents with late-stage cancer who have children aged 5 to 17. The programs were designed to help parents talk with their children about cancer and improve family coping. The goal was to reduce parents' anxiety and depression and boo…

This study tested whether providing palliative care at home, through primary care clinics, helps seriously ill patients with cancer, heart failure, or COPD feel better. About 35 patients were enrolled, and researchers measured symptoms, anxiety, and depression. The goal was to im…

This study tested a web-based tool called eGAP designed to help older cancer patients (65+), their caregivers, and doctors assess the patient's overall health and needs. The goal was to see if the platform was easy to use and practical in a real-world clinic. The study was stoppe…

This study looked at whether digital health tools (like smartphone apps) could help people on cancer treatment feel better and use fewer healthcare resources. It included 49 adults with certain cancers who were starting or had completed treatment. The study was stopped early, so …

This study looked at how chemicals in everyday products and the environment might affect cancer risk in pregnant women and their children. Researchers measured chemical levels in the body and checked for signs of inflammation and DNA damage. The study included over 1,500 pregnant…

This study screened cancer patients for genetic markers that affect how they respond to drugs. The goal was to use this information to quickly match patients to the right clinical trials and drug doses, saving time. Only 8 adults participated before the study ended. It was design…

This study aimed to understand how COVID-19 affects people with cancer. Researchers checked how many cancer patients had COVID-19 without symptoms and how their immune systems responded. The study included 83 patients but was stopped early.

This study created a registry for people who survived cancer as young adults (ages 18-39). Researchers wanted to understand their levels of depression, anxiety, social support, and financial stress. Participants filled out online surveys every 6 to 12 months. The registry also he…

This study aimed to find the best cell source for creating a non-stick patch to prevent adhesions in cancer patients. Researchers compared cells from the peritoneum and from fat tissue, growing them in a lab to see which formed the right type of cells. The study was terminated ea…

This study collected fluid from the abdomen or lungs, plus blood, from 22 adults with solid tumors. The goal was to learn more about how cancer works, not to test a new treatment. The information gathered may help researchers develop better ways to fight cancer in the future.