Simple smell and taste exercises may bring flavor back to cancer patients' meals

NCT ID NCT07258589

Recruiting now Symptom relief Sponsor: University Medical Center Groningen Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jul 16, 2026 · Updated 3 times

Summary

This study tests whether a 12-week at-home taste and smell training program can improve taste function in cancer patients who experience taste changes from tyrosine kinase inhibitors. Ninety participants across 12 Dutch hospitals will be randomly assigned to the training or standard care. Researchers will measure taste and smell before and after the program, along with food enjoyment and other outcomes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: taste and smell training
What this could lead to: If it works, this simple at-home training could help cancer patients enjoy food more and reduce taste problems caused by their medication.
What could go wrong: This is a small, early-stage trial with only 90 participants, and the training may not improve taste or smell for everyone. Results may not apply to all cancer patients.

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Conditions

The condition(s) this trial relates to.

cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ONCOLOGICAL PATIENTS PATIENTS WHO ARE TREATED WITH TYROSINE KINASE INHIBITORS TYROSINE KINASE INHIBITOR

Contacts and locations

Locations

Amsterdam UMC
RECRUITING

Amsterdam, Netherlands
Ikazia Ziekenhuis
RECRUITING

Rotterdam, Netherlands
Isala Klinieken
NOT_YET_RECRUITING

Zwolle, Netherlands
Martini Ziekenhuis
RECRUITING

Groningen, Netherlands
Maxima Medisch Centrum
NOT_YET_RECRUITING

Veldhoven, Netherlands
Ommelander Ziekenhuis Groningen
RECRUITING

Scheemda, Netherlands
Radboud University medical Center
NOT_YET_RECRUITING

Nijmegen, Netherlands
Rijnstate Ziekenhuis
NOT_YET_RECRUITING

Arnhem, Netherlands
University Medical Center Groningen
RECRUITING

Groningen, 9713 GZ, Netherlands
Van Weel-Bethesda Ziekenhuis
NOT_YET_RECRUITING

Dirksland, Netherlands
Ziekenhuisvoorzieningen Gelderse Vallei
RECRUITING

Ede, Netherlands

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