Smart CAR t cells take aim at Hard-to-Treat cancers
NCT ID NCT06682793
First seen Oct 31, 2025 · Last updated May 12, 2026 · Updated 21 times
Summary
This study tests a new treatment called A2B395 for adults with advanced solid tumors (like colorectal, lung, breast, and kidney cancers) that have not responded to standard therapy. The treatment uses specially engineered immune cells designed to kill cancer cells while protecting healthy cells. The study has two phases: first, finding a safe dose, and second, checking if the treatment shrinks tumors.
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This is a summary of
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Banner MD Anderson Cancer Center
RECRUITINGGilbert, Arizona, 85234, United States
Contact Email: •••••@•••••
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Fred Hutch Cancer Center
RECRUITINGSeattle, Washington, 98109, United States
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Contact Email: •••••@•••••
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Mayo Clinic
RECRUITINGJacksonville, Florida, 32224, United States
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Mayo Clinic
RECRUITINGRochester, Minnesota, 55905, United States
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Moffitt Cancer Center
RECRUITINGTampa, Florida, 33606, United States
Contact Email: •••••@•••••
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NYU Langone Health
RECRUITINGNew York, New York, 10016, United States
Contact Email: •••••@•••••
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The Ohio State University
RECRUITINGColumbus, Ohio, 43210, United States
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UCLA Medical Center
RECRUITINGLos Angeles, California, 90404, United States
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Contact Email: •••••@•••••
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UCSD Moores Cancer Center
RECRUITINGLa Jolla, California, 92093, United States
Contact Email: •••••@•••••
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Washington University
RECRUITINGSt Louis, Missouri, 63110, United States
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Conditions
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