Deep gene search aims to uncover why some young people get cancer

NCT ID NCT04141462

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at people who developed cancer at a young age (before 40, or before 30 for breast cancer) but had normal results on standard genetic tests. Researchers will use a more advanced technique called exome sequencing to search for new genetic changes that might raise cancer risk. The goal is to find hidden hereditary factors that current tests miss.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could identify new genes linked to early-onset cancer, improving genetic testing and risk assessment for future patients.

What could go wrong

This is an observational study, not a treatment trial. It may not find new genes, and any discoveries would need further validation before helping patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cancer inherited disease susceptibility neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • CH de Troyes

    NOT_YET_RECRUITING

    Troyes, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHRU Jean Minjoz

    NOT_YET_RECRUITING

    Besançon, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU de Dijon

    NOT_YET_RECRUITING

    Dijon, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU de Reims

    NOT_YET_RECRUITING

    Reims, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Centre Georges-François Leclerc

    RECRUITING

    Dijon, 21000, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Polyclinique de Courlancy

    NOT_YET_RECRUITING

    Reims, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••