Can a radioactive tracer reveal whether immunotherapy is working?
NCT ID NCT07724535
First seen Jul 24, 2026 · Last updated Jul 24, 2026
Summary
This trial is investigating whether a new radioactive tracer called 18F-grazy-02, used with PET/CT scans, can safely and effectively monitor how well immunotherapy is working in people with lymphoma or solid tumors. The tracer targets granzyme B, a protein released by immune cells when they attack cancer. By measuring tracer uptake in tumors, doctors hope to see early signs of treatment response. The study includes 30 participants and will also track any side effects from the tracer itself.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- a radioactive tracer called 18F-grazy-02, used for PET/CT imaging
- What this could lead to
- If successful, this imaging method could help doctors see early whether immunotherapy is working, potentially guiding treatment decisions without invasive biopsies.
- What could go wrong
- This is an early-phase trial with only 30 participants, so the tracer's accuracy and safety are still being tested. It may not reliably predict treatment response in all patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Peking University Cancer Hospital & Institute
Beijing, Beijing Municipality, 100142, China
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