Could a nurse-led online therapy beat severe fatigue in advanced cancer?
NCT ID NCT06511518
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This trial investigates whether an online, nurse-guided version of cognitive behavioral therapy (CBT) can reduce severe fatigue in people with advanced cancer who are receiving palliative systemic treatment. Participants complete a 12-week online CBT program with support from their nurse, after an initial session with a psychologist. Researchers compare the results to earlier studies where psychologists delivered the therapy face-to-face, aiming to see if the simpler approach works just as well.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- cognitive behavioral therapy (CBT)
- What this could lead to
- If successful, this could make effective fatigue relief more accessible for people with advanced cancer by shifting therapy from psychologists to nurses and online delivery.
- What could go wrong
- The study is small (56 participants) and compares results to past trials rather than a direct control group, so benefits may not hold up in larger, real-world settings.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Medical Psychology
RECRUITINGAmsterdam, North Holland, 1105AZ, Netherlands
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Other studies related to the condition(s) this trial covers.
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