Could a nurse-led online therapy beat severe fatigue in advanced cancer?

NCT ID NCT06511518

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This trial investigates whether an online, nurse-guided version of cognitive behavioral therapy (CBT) can reduce severe fatigue in people with advanced cancer who are receiving palliative systemic treatment. Participants complete a 12-week online CBT program with support from their nurse, after an initial session with a psychologist. Researchers compare the results to earlier studies where psychologists delivered the therapy face-to-face, aiming to see if the simpler approach works just as well.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

cognitive behavioral therapy (CBT)

What this could lead to

If successful, this could make effective fatigue relief more accessible for people with advanced cancer by shifting therapy from psychologists to nurses and online delivery.

What could go wrong

The study is small (56 participants) and compares results to past trials rather than a direct control group, so benefits may not hold up in larger, real-world settings.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cancer glioma neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Medical Psychology

    RECRUITING

    Amsterdam, North Holland, 1105AZ, Netherlands

    Contact Phone: •••-•••-•••• Email: •••••@•••••